MRI measurement of the canine auditory pathways and relationship with brainstem auditory evoked responses

R. Poma; H. Chambers; R. C. da Costa; N. B. Konyer; S. Nykamp; H. Dobson; N. W. Milgram

doi:10.1055/s-0037-1617367

Veterinary and Comparative Orthopaedics and Traumatology, Inhaltsverzeichnis

Vet Comp Orthop Traumatol 2008; 21(03): 238-242
DOI: 10.1055/s-0037-1617367

Original Research

Schattauer GmbH

MRI measurement of the canine auditory pathways and relationship with brainstem auditory evoked responses

Authors

R. Poma

¹Department of Clinical Studies, University of Guelph, Guelph, Ontario, Canada
H. Chambers

²Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada
R. C. da Costa

³Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus, Ohio, USA
N. B. Konyer

⁴Brain-body Institute, St. Joseph Health Care, Hamilton, Ontario, Canada
S. Nykamp

¹Department of Clinical Studies, University of Guelph, Guelph, Ontario, Canada
H. Dobson

¹Department of Clinical Studies, University of Guelph, Guelph, Ontario, Canada
N. W. Milgram

⁵CanCog Technologies Inc., Toronto, Ontario, Canada

Abstract

Summary

The objective of this study was to determine direct measurements of auditory pathways by magnetic resonance imaging (MRI) during the growth period of healthy Beagles, and to discover how canine brainstem auditory evoked response (BAER) latencies vary in relation to these MRI measurements. Eighty healthy Beagles were tested at eight, 16 and 52 weeks of age (stages 1, 2, 3, respectively) with BAER and brain MRI. The BAER interpeak latency (IPL) II-V and brain MRI neural generators of BAER waves II and V were identified. A linear distance was calculated in millimeters in order to determine the approximate length of auditory pathways. Sensory nerve conduction velocity (SNCV) of the auditory pathway between peak II and peak V was calculated for each group. A significant difference was observed between brain MRI distances among the three stages. Mean BAER IPL II-V were not significantly different between the three stages. The progressive growth of the skull and brain witnessed by the progressive increased distance of the MRI auditory pathways between peak II and peak V was not associated with a progressive maturation of the BAER IPL II-V. The SNCV of the auditory pathway between peak II and peak V was 6.14 m/sec for group 1; 6.76 m/sec for group 2; and 7.32 m/sec for group 3.

Keywords

Auditory pathways - canine - magnetic Resonance Imaging - brainstem auditory evoked response (BAER)

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Referenzen

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