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Nuklearmedizin 1977; 16(02): 57-62
DOI: 10.1055/s-0037-1620606
Originalarbeiten – Original Articles
Schattauer GmbH

A Simple and Rapid Non-Invasive Radioisotope Method to Determine Ventricular Ejection Fractions and Cardiopulmonary Transit Times

J. Kuikka
1   From the Division of Nuclear Medicine (Head: A. Ahonen,) of the Department of Clinical Chemistry (Director: R. Vihko, Professor of Clinical Chemistry), University Central Hospital, Oulu, Finland
,
A. Ahonen
1   From the Division of Nuclear Medicine (Head: A. Ahonen,) of the Department of Clinical Chemistry (Director: R. Vihko, Professor of Clinical Chemistry), University Central Hospital, Oulu, Finland
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Received:08. November 1976

Publikationsdatum:
10. Januar 2018 (online)

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Summary

Ejection fractions and cardiopulmonary transit times were measured in 20 hospital patients by means of intravenously injected 99mTc-radiocardiography. Time activity curves from the regions of the whole heart, superior vena cava, right atrium, right ventricle, right lung, left atrium and left ventricle were drawn and analyzed by using the modified gamma function fitting method. The comparison between the ejection fractions determined from the whole heart curves and those from the ventricular curves shows a correlation coefficient of 0.93 for the right ventricle and of 0.90 for the left, although there was a systematic difference between the determinations. The analysis of the single ventricular curves gave about 10 per cent higher values than those obtained from the whole heart curves

The cardiopulmonary parameters measured from the whole heart curves for 16 normal subjects the following results gave:

right ventricular ejection fraction = 0.57 ± 0.08

left ventricular ejection fraction = 0.62 ± 0.08

pulmonary mean transit time = 6.1 ± 1.1 heart-beats

intracardiac mean transit time = 10.5 ± 1.8 heartbeats

right/left ventricular volume = 1.10 ± 0.09

These values agree closely with the data accumulated using more elaborate methods. The method presented here is simple to perform, it is non-invasive, time-saving, inexpensive, easy to analyze and suitable for exercising subjects and for bed-side measurements. Data assembly and analysis are easily automated so that results are obtainable immediately after measurements.

 

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