Immunbedingte Neutropenie bei einem Malteser-Rüden

Zusammenfassung:

Gegenstand und Ziel: Der Fallbericht erörtert diagnostisches Vorgehen und Therapie bei einem Hund mit einer immunbedingten Neutropenie. Material und Methode: Beschreibung der Krankengeschichte eines 4,5 Jahre alten Rüden, der 14 Tage nach einer Auffrischungsimpfung mit Symptomen einer Septikämie und hochgradiger Neutropenie vorgestellt wurde. Ergebnisse: Nach Ausschluss anderer Erkrankungen und anhand des Nachweises von Antikörpern auf den neutrophilen Granulozyten wurde eine immunbedingte Neutropenie diagnostiziert und erfolgreich mit Kortikosteroiden behandelt. Schlussfolgerungen und Klinische Relevanz: Immunbedingte Neutropenien sind beim Hund selten und können unterschiedliche Ursachen aufweisen. Das Auftreten der immunbedingten Neutropenie nach einer Auffrischungsimpfung könnte im vorliegenden Fall auf eine impfassoziierte Ätiologie hindeuten.

Summary

Objective: This case report details the diagnostic approach and therapy in a patient with immune-mediated neutropenia. Material and methods: History of a 4.5-year-old male dog presented 14 days after routine booster vaccination with symptoms of septicaemia and severe neutropenia. Results: By excluding other causes of neutropenia and detection of antibodies on the surface of neutrophils an immune-mediated neutropenia was diagnosed and successfully treated with corticosteroids. Conclusion and Clinical relevance: Immune-mediated neutropenias in dogs are rare and can be associated with various etiologies. Since the immune-mediated neutropenia in this case occurred shortly after a vaccination, an etiologic connection was suspected.

Schlüsselwörter

Hund - immunvermittelte Erkrankungen - Neutropenie - antigranulozytäre Antikörper

Key words

Dog - immune-mediated diseases - neutropenia - anti-granulocytic antibodies

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