Subscribe to RSS
DOI: 10.1055/s-0038-1623137
Hämoplasmeninfektion bei einer Milchkuh
Haemoplasma infection in a dairy cowPublication History
Eingegangen:
23 March 2012
Akzeptiert nach Revision:
24 May 2012
Publication Date:
06 January 2018 (online)
![](https://www.thieme-connect.de/media/10.1055-s-00034912/201206/lookinside/thumbnails/10-1055-s-0038-1623137_de-1.jpg)
Zusammenfassung
Die Arbeit beschreibt die klinische und labordiagnostische Untersuchung und Behandlung einer 7 Jahre alten Rotfleckviehkuh mit reduzierter Fresslust und Milchleistung sowie auffällig blassgelb verfärbter Haut und Schleimhaut. Die labordiagnostische Untersuchung ergab eine hochgradige regenerative Anämie und eine Hyperbilirubinämie. Mittels PCR ließen sich die Hämoplasmenarten Mycoplasma wenyonii und ,Candidatus Mycoplasma haemobos’ im Blut nachweisen. Unter der Therapie mit Oxytetrazyklin verbesserten sich der Allgemeinzustand und die Milchleistung der Kuh schnell. Bei der Untersuchung der Blutproben aller 23 Tiere im Bestand konnten bei 15 Kühen beide Hämoplasmenarten, bei drei nur ,Candidatus Mycoplasma haemobos’ und bei einer Kuh nur Mycoplasma wenyonii nachgewiesen werden. Von den drei getesteten Kälbern erwiesen sich zwei als positiv für ,Candidatus Mycoplasma haemobos’. Mit Ausnahme der oben erwähnten Kuh waren alle Tiere klinisch gesund.
Summary
The present work describes the clinical and laboratory examination as well as the treatment of a 7-year-old local dairy breed cow presented with reduced appetite, decreasing milk yield and striking yellowish discoloured skin and mucosa. The laboratory examination revealed a high degree regenerative anaemia and hyperbilirubinaemia. The bovine haemotrophic mycoplasma species Mycoplasma wenyonii and ‘Candidatus Mycoplasma haemobos’ were detected in the blood by PCR. Treatment with oxytetracycline rapidly improved the general condition, and milk production was increased. In a follow-up study, blood samples of all 23 animals from the same herd were examined. Fifteen cows were found to be infected with both haemoplasma species, three animals were only infected with ‘Candidatus Mycoplasma haemobos’ and one animal only with Mycoplasma wenyonii. Two out of three tested calves were positive for ‘Candidatus Mycoplasma haemobos’. Except for the above described anaemic cow, all other animals were clinically healthy.
-
Literatur
- 1 Adler S, Ellenbogen V. A note on two new blood parasites of cattle, Eperythrozoon and Bartonella. J Comp Path Ther 1934; 47: 219-221.
- 2 Genova SG, Streeter RN, Velguth KE, Snider TA, Kocan KM, Simpson KM. Severe anemia associated with Mycoplasma wenyonii infection in a mature cow. Can Vet J 2011; 52: 1018-1021.
- 3 Hoelzle K, Winkler M, Kramer MM, Wittenbrink MM, Dieckmann SM, Hoelzle LE. Detection of Candidatus Mycoplasma haemobos in cattle with anaemia. Vet J 2010; 187: 408-410.
- 4 Hofmann-Lehmann R, Meli ML, Dreher UM, Gonczi E, Deplazes P, Braun U, Engels M, Schüpbach J, Jörger K, Thoma R, Griot C, Stärk KD, Willi B, Schmid J, Kocan KM, Lutz H. Concurrent infections with vectore-borne pathogens associated with fatal hemolytic anemia in a cattle herd in Switzerland. J Clin Microbiol 2004; 42: 3775-3780.
- 5 Hornok S, Micusutka A, Fernández de Mera IG, Meli ML, Gönczi E, Tánczos B, Mangold AJ, Farkas R, Lutz H, Hofmann-Lehmann R, de la Fuente J. Fatal bovine anaplasmosis in a herd with new genotypes of Anaplasma marginale, Anaplasma ovis and concurrent haemoplasmosis. Res Vet Sci 2012; 92: 30-35.
- 6 Hornok S, Micsutka A, Meli ML, Lutz H, Hofmann-Lehmann R. Molecular investigation of transplacental and vector-borne transmission of bovine haemoplasmas. Vet Microbiol 2011; 152: 411-414.
- 7 Meli ML, Willi B, Dreher UM, Cattori V, Knubben-Schweizer G, Nuss K, Braun U, Lutz H, Hofmann-Lehmann R. Identification, molecular characterization, and occurrence of two bovine hemoplasma species in Swiss cattle and development of real-time TaqMan quantitative PCR assays for diagnosis of bovine hemoplasma infections. J Clin Microbiol 2010; 48: 3563-3568.
- 8 Messick JB. Hemotrophic mycoplasmas (hemoplasmas): a review and new insights into pathogenic potential. Vet Clin Pathol 2004; 33: 2-13.
- 9 Montes AJ, Wolfe DF, Welles EG, Tyler JW, Tepe E. Infertility associated with Eperythrozoon wenyonii infection in a bull. J Am Vet Med Assoc 1994; 204: 261-263.
- 10 Neimark H, Johansson KE, Rikihisa Y, Tully JG. Proposal to transfer some members of the genera Haemobartonella and Eperythrozoon to the genus Mycoplasma with descriptions of ‘Candidatus Mycoplasma haemofelis’, ‘Candidatus Mycoplasma haemomuris’, ‘Candidatus Mycoplasma haemosuis’ and ‘Candidatus Mycoplasma wenyonii’. Int J Syst Evol Microbiol 2001; 51: 891-899.
- 11 Neimark H, Johansson KE, Rikihisa Y, Tully JG. Revision of haemotrophic Mycoplasma species names. Int J Syst Evol Microbiol 2002; 52: 683.
- 12 Radostits OM, Gay CC, Hinchcliff KW, Constable PD. Diseases associated with Rickettsiales. In: Veterinary Medicine. A Textbook of the Diseases of Cattle, Horses, Sheep, Pigs, and Goats. Philadelphia: Saunders Elsevier; 2007: 1458.
- 13 Smith JA, Thrall MA, Smith JL, Salman MD, Ching SV, Collins JK. Eperythrozoon wenyonii infection in dairy cattle. J Am Vet Med Assoc 1990; 196: 1244-1250.
- 14 Tagawa M, Matsumotot K, Inokuma H. Molecular detection of Mycoplasma wenyonii and ‘Candidatus Mycoplasma haemobos’ in cattle in Hokkaido. Japan Vet Microbiol 2008; 132: 177-180.
- 15 Veterinärmedizinisches Labor, Departement für Nutztiere, Vetsuisse-Fakultät Zürich. Laboreigene Referenzwerte.