D-lactate elevation as a cause of metabolic acidosis in newborn goat kids

C. Klein; H. Bostedt; A. Wehrend

doi:10.1055/s-0038-1624003

Tierärztliche Praxis Ausgabe G: Großtiere / Nutztiere, Table of Contents

Tierarztl Prax Ausg G Grosstiere Nutztiere 2010; 38(06): 371-376
DOI: 10.1055/s-0038-1624003

Case Report

Schattauer GmbH

D-lactate elevation as a cause of metabolic acidosis in newborn goat kids

The potential role of milk ingestion as etiopathogenetic factorMetabolische Azidose durch erhöhte D-Laktat-Blutwerte bei neugeborenen Ziegenlämmern. Muttermilchaufnahme als potenzieller ätiopathogenetischer Faktor

C. Klein

¹College of Agriculture, Department of Veterinary Science, University of Kentucky, USA

,

H. Bostedt

²Clinic for Obstetrics, Gynecology and Andrology of Large and Small Animals with Ambulatory Service, Justus-Liebig-University Giessen, Germany

,

A. Wehrend

²Clinic for Obstetrics, Gynecology and Andrology of Large and Small Animals with Ambulatory Service, Justus-Liebig-University Giessen, Germany

› Author Affiliations

Abstract

Full Text

References

References
1 Bleul U, Schwantag S, Stocker H, Corboz I, Grimm F, Engels M, Borel N, Lutz H, Schoenmann M, Kaehn W. Floppy kid syndrome caused by D-lactic acidosis in goat kids. J Vet Med 2006; 20: 1003-1008.
2 Bostedt H. Untersuchungsmethoden und Diagnostik. In: Schaf- und Ziegenkrankheiten, 2nd ed. Bostedt H, Dedie K. eds. Stuttgart: Ulmer; 1996: 17-30.
3 Christopher M, Eckfeldt J, Eaton J. Propylene glycol ingestion causes D-lactic acidosis. Lab Investig 1990; 62: 114-118.
4 Dercksen DP, Counotte GH, Hazebroek MK, Arts W, van Rijn T. Selenium requirements of dairy goats. Tijdschr Diergeneeskd 2007; 132 (Suppl. 12) 468-471.
5 Dunlop RH. Pathogenesis of ruminal lactic acidosis. Adv Vet Sci Comp Med 1972; 16: 259-302.
6 Felipe A, Remesar X, Pastor-Anglada M. L-lactate uptake by rat liver. Effect of food deprivation and substrate availability. Biochem J 1991; 273: 195-198.
7 Garvie EI. Bacterial Lactate Dehydrogenases. Microbiol Rev 1980; 44 (Suppl. 21) 106-139.
8 Genitle A, Sconza S, Lorenz I. et al. D-lactic acidosis in calves as a consequence of experimentally induced ruminal acidosis. J Vet Med A 2004; 51: 64-70.
9 Giesecke D, Stangassinger M. Genesis and biochemistry of rumen acidosis. 7. Oxydation rate and quantitative gluconeogenesis from D-lactate-(14C) in goats. Zentralbl Veterinärmed A 1979; 26 (Suppl. 02) 85-94.
10 Guffler H, Pernthaner A. ,,Neonatales Laehmungssyndrom“ bei Ziegenkitzen: Folge einer metablischen Azidose. Wien Tieraerztl Mschr 1999; 86: 382-389.
11 Huckabee WE. Relationship of pyruvate and lactate during anaerobic metabolism. II. Exercise and formation of O2-debt. J Clin Invest 1958; 37 (Suppl. 02) 255-263.
12 Lorenz I. Influence of D-lactate on metabolic acidosis and on prognosis in neonatal calves with diarrhoea. J Vet Med A 2004; 51: 425-428.
13 Packer RA, Cohn LA, Wohlstadter DR, Shelton GD, Naylor JM, Zello GA, Ewaschuk JB, Williams DA, Ruaux CG, O’Brien DP. D-Lactic Acidosis Secondary to Exocrine Pancreatic Insufficiency in a Cat. J Vet Int Med 2008; 19 (Suppl. 01) 106-110.
14 Riet-Correa F, Tabosa IM, Vasoncelos J. et al. Floppy Kid Syndrome. Pesq Vet Bras 2004; 24: 111-113.
15 Schelcher F, Marcillaud S, Braun JP. et al. Metabolic acidosis without dehydration and no or minimal diarrhea in nurseler calves is caused by hyper D-lactatemia. Proceedings XX World Buiatrics Congress 1998: 371-374.
16 Stangassinger M, Giesecke D. Origin and biochemistry of rumen acidosis. 6. Renal excretion of lactic acid isomers. Zentralbl Veterinärmed A 1978; 25 (Suppl. 08) 597-607.
17 Stolberg L, Rolfe R, Gittlin N. et al. D-lactic acidosis due to abnormal gut flora: diagnosis and treatment of two cases. N Engl J Med 1982; 306: 1344-1348.
18 Tremblay R, Butler D, Allen J. et al. Metabolic acidosis without dehydration in seven goat kids. Can Vet J 1991; 32: 308-301.
19 Zhang DL, Jiang ZW, Jiang J, Cao B, Li JS. D-lactic acidosis secondary to short bowel syndrome. Postgrad Med J 2003; 79: 110-112.