Evaluation of Arterial Injury Due to Balloon Angioplasty by ¹¹¹In-Labelled Platelets

The sensitivity of ¹¹¹In-labelled platelets for the detection of intimai trauma following balloon angioplasty was evaluated in 8 arteries in 6 patients. Focal platelet accumulation was detected at all 3 iliacs, one superficial femoral and the anterior tibial artery angioplasty sites. Minimal platelet accumulation was present at the superficial femoral artery angioplasty site in another patient whereas in both renal arteries no focal platelet accumulation was detectable. These results indicate that ¹¹¹In-labelled platelets may provide a sensitive method for evaluation platelet accumulation at the balloon angioplasty site in the peripheral circulation.

Die Empfindlichkeit der ¹¹¹In-markierten Thrombozyten in der Auffindung von Verletzungen der Intima nach Ballonangioplastik wurde an 8 Arterien bei 6 Patienten untersucht. Eine lokale Plättchenakkumulation an der Stelle der Angioplastik wurde bei allen 3 A. iliacae und bei der vorderen Tibialarterie entdeckt. Eine minimale Plättchenanreicherung war an der Angioplastikstelle der A. Femoralis superficialis eines anderen Patienten vorhanden, während in den beiden Nierenarterien keine lokale Akkumulation gefunden wurde. Diese Ergebnisse zeigen, daß ¹¹¹In-markierte Thrombozyten eine empfindliche Methode zur Beurteilung einer Plättchenspeicherung an der Stelle einer Ballonangioplastik im peripheren Kreislauf liefern könnten.

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