Outcomes of Preterm Infants with a Periventricular Venous Infarction in the Neonatal Period

Rudaina Banihani; Paige T. Church; Maureen Luther; Alex Kiss; Elizabeth V. Asztalos

doi:10.1055/s-0038-1624575

Journal of Pediatric Neurology, Table of Contents

Journal of Pediatric Neurology 2019; 17(02): 057-064
DOI: 10.1055/s-0038-1624575

Original Article

Georg Thieme Verlag KG Stuttgart · New York

Outcomes of Preterm Infants with a Periventricular Venous Infarction in the Neonatal Period

Rudaina Banihani

¹Department of Newborn and Developmental Pediatrics, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada

,

Paige T. Church

¹Department of Newborn and Developmental Pediatrics, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada

,

Maureen Luther

²Neonatal Follow-Up Clinic, Women & Babies Program, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada

,

Alex Kiss

³Sunnybrook Research Institute, University of Toronto, Toronto, Ontario, Canada

,

Elizabeth V. Asztalos

¹Department of Newborn and Developmental Pediatrics, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada

› Author Affiliations

Abstract

We compared the neurodevelopmental outcomes of infants with and without a periventricular venous hemorrhagic infarction (PVHI). The study was designed as a case–control study. The primary outcome measure was any score of < 85 in at least one of the cognition, language, or motor domains of the Bayley Scales of Infant and Toddler Development-3rd edition (Bayley-III) at 18 to 24 months corrected age. Of 41 infants identified, 20 index infants were matched with 40 controls for analyses. No differences in the primary outcome were noted between the two groups of infants, 52.9% with PVHI compared with 62.5% without PVHI (OR: 0.68, 95% CI: 0.21–2.13; p = 0.56). Infants with a PVHI were likely to have cerebral palsy, 85% compared with 7.5%, with the majority (70%) being ambulatory. Infants with a PVHI were developmentally similar to their preterm counterparts as it related to cognition and language.

Keywords

periventricular venous infarct - neurodevelopment outcomes - preterm infants

Full Text

References

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