Does Donor Age of Nonirradiated Achilles Tendon Allograft Influence Mid-Term Results of Revision ACL Reconstruction?

Stefano Zaffagnini; Tommaso Roberti di Sarsina; Tommaso Bonanzinga; Marco Nitri; Luca Macchiarola; Federico Stefanelli; Gianandrea Lucidi; Alberto Grassi

doi:10.1055/s-0038-1626739

Joints, Table of Contents

CC-BY-NC-ND 4.0 · Joints 2018; 06(01): 010-015
DOI: 10.1055/s-0038-1626739

Original Article

Georg Thieme Verlag KG Stuttgart · New York

Does Donor Age of Nonirradiated Achilles Tendon Allograft Influence Mid-Term Results of Revision ACL Reconstruction?

Authors

Stefano Zaffagnini

¹II Clinica Ortopedica e Traumatologica, Istituto Ortopedico Rizzoli, Bologna, Italy

²Laboratorio di Biomeccanica ed Innovazione Tecnologica, Istituto Ortopedico Rizzoli, Bologna, Italy
Tommaso Roberti di Sarsina

¹II Clinica Ortopedica e Traumatologica, Istituto Ortopedico Rizzoli, Bologna, Italy

²Laboratorio di Biomeccanica ed Innovazione Tecnologica, Istituto Ortopedico Rizzoli, Bologna, Italy
Tommaso Bonanzinga

¹II Clinica Ortopedica e Traumatologica, Istituto Ortopedico Rizzoli, Bologna, Italy

²Laboratorio di Biomeccanica ed Innovazione Tecnologica, Istituto Ortopedico Rizzoli, Bologna, Italy
Marco Nitri

¹II Clinica Ortopedica e Traumatologica, Istituto Ortopedico Rizzoli, Bologna, Italy

²Laboratorio di Biomeccanica ed Innovazione Tecnologica, Istituto Ortopedico Rizzoli, Bologna, Italy
Luca Macchiarola

¹II Clinica Ortopedica e Traumatologica, Istituto Ortopedico Rizzoli, Bologna, Italy

²Laboratorio di Biomeccanica ed Innovazione Tecnologica, Istituto Ortopedico Rizzoli, Bologna, Italy
Federico Stefanelli

¹II Clinica Ortopedica e Traumatologica, Istituto Ortopedico Rizzoli, Bologna, Italy

²Laboratorio di Biomeccanica ed Innovazione Tecnologica, Istituto Ortopedico Rizzoli, Bologna, Italy
Gianandrea Lucidi

²Laboratorio di Biomeccanica ed Innovazione Tecnologica, Istituto Ortopedico Rizzoli, Bologna, Italy
Alberto Grassi

¹II Clinica Ortopedica e Traumatologica, Istituto Ortopedico Rizzoli, Bologna, Italy

²Laboratorio di Biomeccanica ed Innovazione Tecnologica, Istituto Ortopedico Rizzoli, Bologna, Italy

Abstract

Purpose The purpose of the present study was to investigate if the donor age of nonirradiated Achilles tendon allograft could influence the clinical results of revision anterior cruciate ligament (ACL) reconstruction.

Methods All patients that underwent ACL revision between 2004 and 2008 with at least 4 years of follow-up were included. For all the patients that met the inclusion criteria, the age of the graft donor was obtained from the tissue bank. Lysholm score was administered to patients that met inclusion criteria. In addition, patients were divided in two groups based on the donor age (<45 years vs. ≥45 years), and the baseline characteristics and outcomes were compared.

Results Fifty-two patients were evaluated at a mean 4.8 ± 0.8 years follow-up with Lysholm score. The Lysholm significantly improved from 62.3 ± 6.6 at preoperative status to 84.4 ± 12.3 at final follow-up. The mean donor age was 48.7 ± 8.4 years; a significant difference in Lysholm score was noted between patients that received an allograft with a donor age <45 years (14 patients; 27%) and those receiving an allograft with a donor age ≥45 years (38; 73%) (89.5 ± 3.2 vs. 80.1 ± 11.1, respectively; p = 0.0469). The multiple regression model showed the donor age, the final follow-up, and the preoperative Lysholm score as significant predictors of postoperative Lysholm score (p < 0.0002).

Conclusion Donor age of nonirradiated Achilles tendon allograft influenced the mid-term results of revision ACL reconstruction, thus advising the use of grafts from young donors.

Level of Evidence Level III, retrospective comparative study.

Keywords

allograft - Achilles tendon - knee - revision - anterior cruciate ligament

Full Text

References

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