Nervenheilkunde 2007; 26(07): 618-622
DOI: 10.1055/s-0038-1626906
Neuroethik & Neurophilosophie
Schattauer GmbH

Eingriff ins Gehirn oder Angriff auf die psychische Integrität?

T. Galert
,
S. Schleim
Further Information

Publication History

Publication Date:
20 January 2018 (online)

 

 
  • Literatur

  • 1 Weniger T. Rückkehr der Psychochirurgie. Deutsches Ärzteblatt 2004; 101: A2597-A2598.
  • 2 Hubig C, Poser H. (eds.). Cognitio humana – Dynamik des Wissens und der Werte. Berlin: Akademischer Verlag; 1997
  • 3 Woerly S, Marchand R. 100 years of Neurotransplantation in the mammalians. Neurochirurgie 1990; 36 (02) 171-95.
  • 4 Das GD, Hallas BH, Das KG. Transplantation of neural tissues in the brains of laboratory mammals – technical details and comments. Experientia 1979; 35 (02) 143-153.
  • 5 Houle JD, Das GD. Freezing of embryonic neural tissue and its transplantation in the rat brain. Brain Research 1980; 192 (02) 570-574.
  • 6 Low WC, Lewis PR, Bunch ST, Dunnett SB, Thomas SR, Iversen SD. et al. Function recovery following neural transplantation of embryonic septal nuclei in adult rats with septohippocampal lesions. Nature 1982; 300 (5889): 260-262.
  • 7 Bjorklund A. Neural transplantation – an experimental tool with clinical possibilities. Trends in Neurosciences 1991; Aug; 14 (08) 319-322.
  • 8 Lindvall O. Neural Transplantation. Cell transplantation 1995; Jul-Aug; 04 (04) 393-400.
  • 9 Shannon KM, Kordower JH. Neural transplantation for Huntington’s disease: Experimental rationale and recommendations for clinical trials. Cell Transplantation 1996; Mar-Apr; 05 (02) 339-352.
  • 10 Lindvall O. Neural transplantation: a hope for patients with Parkinson’s disease. Neuroreport 1997; Sep; 08 (14) R3-R10.
  • 11 Johansson BB, Grabowski M. Functional recovery after brain infarction – plasticity and neural transplantation. Brain Pathology 1994; Jan; 4 (01) 85-95.
  • 12 Kondziolka D, Wechsler L, Achim C. Neural transplantation for stroke. Journal of Clinical Neuroscience 2002; May; 09 (03) 225-230.
  • 13 Kondziolka D, Steinberg GK, Wechsler L, Meltzer CC, Elder E, Gebel J. et al. Neurotransplantation for patients with subcortical motor stroke: a phase 2 randomized trial. Journal of Neurosurgery 2005; Jul; 103 (01) 38-45.
  • 14 Wennersten A, Meijer X, Holmin S, Wahlberg L, Mathiesen T. Proliferation, migration, and differentiation of human neural stem/progenitor cells after transplantation intoa rat model of traumatic brain injury. Journal of Neurosurgery 2004; Jan; 100 (01) 88-96.
  • 15 Olanow CW, Goetz CG, Kordower JH, Stoessl AJ, Sossi V, Brin MF. et al. A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson’s disease. Annals of Neurology 2003; Sep; 54 (03) 403-414.
  • 16 Freed CR, Greene PE, Breeze RE, Tsai WY, Du-Mouchel W, Kao R. et al. Transplantation of embryonic dopamine neurons for severe Parkinson’s disease. New England Journal of Medicine 2001; Mar; 344 (10) 710-719.
  • 17 Bachoud-Levi A, Remy P, Nguyen JP, Brugieres P, Lefaucheur JP, Bourdet C. et al. Motor and cognitive improvements in patients with Huntington’s disease after neural transplantation. Lancet 2000; Dec; 356 (9246): 1975-1979.
  • 18 Hagell P, Piccini P, Bjorklund A, Brundin P, Rehncrona S, Widner H. et al. Dyskinesias following neural transplantation in Parkinson’s disease. Nature Neuroscience 2002; Jul; 05 (07) 627-628.
  • 19 Boer GJ. Ethical guidelines for the use of human embryonic or fetal tissue for experimental and clinical neurotransplantation and research. Journal of Neurology 1994; Dec; 242 (01) 1-13.
  • 20 http://www.nectar-org.eu
  • 21 Bei diesen wird auf Hirngewebe von Schweineembryonen zurückgegriffen. Deacon T, Schumacher J, Dinsmore J, Thomas C, Palmer P, Kott S. et al. Histological evidence of fetal pig neural cell survival after transplantation into a patient with Parkinson’s disease. Nature Medicine 1997; Mar; 03 (03) 350-353.
  • 22 Boethius J, Meyerson BA. Treatment of benign and malignant pain by chronic deep brain-stimulation. Acta Neurochirurgica 1977; 37 (3–4): 298.
  • 23 Plotkin R. Results in 60 cases of deep brain-stimulation for chronic intractable pain. Applied Neurophysiology 1982; 45 (1–2): 173-178.
  • 24 Mundinger F. Deep brain-stimulation in pyramidal and extrapyramidal motor disorders, spasticity and dyskinesias. Physics in Medicine and Biology 1980; 25 (05) 992.
  • 25 Ondo W, Jankovic J, Schwartz K, Almaguer M, Simpson RK. Unilateral thalamic deep brain stimulation for refractory essential tremor and Parkinson’s disease tremor. Neurology 1998; Oct; 51 (04) 1063-1069.
  • 26 Kumar R, Lozano AM, Kim YJ, Hutchison WD, Sime E, Halket E. et al. Double-blind evaluation of subthalamic nucleus deep brain stimulation in advanced Parkinson’s disease. Neurology 1998; Sep; 51 (03) 850-855.
  • 27 Deuschl G, Schade-Brittinger C, Krack P, Volkmann J, Schafer H, Botzel K. et al. A randomized trial of deep-brain stimulation for Parkinson’s disease. New England Journal of Medicine 2006; Aug; 355 (09) 896-908.
  • 28 Bejjani BP, Damier P, Arnulf I, Thivard L, Bonnet AM, Dormont D. et al. Transient acute depression induced by high-frequency deep-brain stimulation. New England Journal of Medicine 1999; May; 340 (19) 1476-1480.
  • 29 Krack P, Kumar R, Ardouin C, Dowsey PL, McVicker JM, Benabid AL. et al. Mirthful laughter induced by subthalamic nucleus stimulation. Movement Disorders 2001; Sep; 16 (05) 867-875.
  • 30 Nuttin B, Cosyns P, Demeulemeester H, Gybels J, Meyerson B. Electrical stimulation in anterior limbs of internal capsules in patients with obsessive-compulsive disorder. Lancet 1999; Oct 30; 354 (9189): 1526.
  • 31 Nuttin BJ, Gabriels LA, Cosyns PR, Meyerson BA, Andreewitch S, Sunaert SG. et al. Long-term electrical capsular stimulation in patients with obsessive-compulsive disorder. Neurosurgery 2003; Jun; 52 (06) 1263-1272.
  • 32 Mayberg HS, Lozano AM, Voon V, McNeely HE, Seminowicz D, Hamani C. et al. Deep brain stimulation for treatment-resistant depression. Neuron 2005; Mar; 45 (05) 651-660.
  • 33 Padberg F, Grossheinrich N, Schonfeldt-Lecuona C, Pogarell O. Update on vagus nerve stimulation and deep brain stimulation in depression. Nervenheilkunde 2006; 25 (08) 635-640.
  • 34 Linke D. Hirnverpflanzung – Die erste Unsterblichkeit auf Erden. Reinbek bei Hamburg: Rowohlt; 1993
  • 35 Galert T. Inwiefern können Eingriffe in das Gehirn die personale Identität bedrohen?. In: Bora A, Decker M, Grunwald A, Renn O. (eds.). Technik in einer fragilen Welt. Berlin: Edition Sigma; 2005: 91-99.
  • 36 Merkel R, Boer G, Fegert F, Galert T, Hartmann D, Nuttin B. et al. Intervening in the Brain. Changing Psyche and Society. Heidelberg: Springer; 2007
  • 37 http://www.europaeische-akademie-aw.de/pages/ arbeitsgruppen_forschung/projektgruppen_interveninginpsychiccapacities
  • 38 Schlaepfer TE. et al. Deep brain stimulation to reward circuitry alleviates anhedonia in refractory major depression. Neuropsychopharmacology. 2007 advance online publication, 11 April 2007; doi:10.1038/sj.npp.1301408.