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Nervenheilkunde 2013; 32(07): 485-492
DOI: 10.1055/s-0038-1628522
DOI: 10.1055/s-0038-1628522
Neuroradiologie
7-Tesla-MRT in der Neuroradiologie
Möglichkeiten und Perspektiven7 Tesla MRI for neuroradiological applicationsPossibilities and perspectivesFurther Information
Publication History
eingegangen am:
14 February 2013
angenommen am:
04 March 2013
Publication Date:
24 January 2018 (online)
Zusammenfassung
Seit Einführung der 7 Tesla (7 T) Ultrahochfeld-MRT (UHF-MRT) in die klinische Forschung werden ihre Anwendungsmöglichkeiten für die neuroradiologische Diagnostik evaluiert. Die 7 T MRT ermöglicht eine Verbesserung der strukturellen und funktionellen Bildgebung aufgrund ihres hohen Signalzu-Rausch-Verhältnisses, der erzielbaren räumlichen Auflösung und ihrer hohen Sensitivität für Suszeptibilitätsartefakte. Akquisitionszeit und Bildqualität erleiden jedoch Verluste durch lokale Magnetfeldinhomogenitäten und die Parameterwahl und Schichtanzahl werden aufgrund der höheren Energiedeposition im Gewebe negativ beeinflusst. Neben den technischen Grundlagen der 7 T UHF-MRT werden neuroradiologische Anwendungsmöglichkeiten bei Hirntumoren, entzündlichen und degenerativen ZNS-Erkrankungen, Epilepsie sowie zerebrovaskulären Erkrankungen aufgezeigt und Möglichkeiten der MR-Spektroskopie, funktionelle MRT und MR-Angiografie betrachtet. Bis zur Einführung der 7 T MRT in die klinische Diagnostik werden Optimierungen von Hard-und Software sowie klinische Studien notwendig sein, um ihre Vorteile für die neuroradiologische Diagnostik bestmöglich nutzen zu können.
Summary
Since the introduction of 7 Tesla (7 T) ultrahigh-field MRI (UHF MRI) into clinical research, its applications for neuroradiological diagnostics are being evaluated. 7 T MRI allows an improvement in structural and functional neuroimaging due to its high signal-to-noise ratio combined with high spatial resolution and sensitivity for susceptibility effects. However, acquisition time and image quality suffer from local inhomogeneities of the magnetic field and the number of slices and choice of sequence parameters is negatively affected by higher energy deposition in the tissue compared to lower field strengths. In addition to the technical fundamentals of 7 T UHF MRI, neuroradiological applications are presented regarding brain tumours, inflammatory and degenerative diseases of the CNS, epilepsy, and cerebrovascular diseases. 7 T MR spectroscopy, functional MRI, and MR angiography are described. Before 7 T MRI can be introduced into clinical diagnostics, further technical adaptations of hardware and software as well as additional research are needed to optimize its practical value for neuroradiological diagnostics.
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