Hirntumortherapie

Zusammenfassung

Die Therapie der primären Hirntumoren erfährt derzeit einen neuen Schub durch dia-gnostisch und therapeutisch relevante Erkenntnisse im molekularen Bereich. Es werden Defekte der Wachstumsregulation definiert, die in ähnlicher Form auch bei anderen malignen Erkrankungen vorkommen. Gegen diese definierten Defekte werden immer mehr zielgerichtete Therapien mit spezifischen Hemmstoffen verfügbar. Dadurch eröffnen sich neue Perspektiven, die Therapie zu verbessern.

Summary

Therapy of primary brain tumours gets a new impact by new insights into the molecular mechanisms of disturbed cell growth. It is possible, to define specific defects of cellular signal transduction cascades, which often use similar in other malignant tumours. Thus specific inhibitors available for other tumours may also be applied in gliomas providing new therapeutic options.

Schlüsselwörter

Gliome - Chemotherapie - molekulare Diagnostik - zielgerichtete Therapie

Keywords

Glioma - chemotherapy - molecular diagnostic - targeted therapy

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