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Nuklearmedizin 1990; 29(01): 35-39
DOI: 10.1055/s-0038-1629510
Originaler Artikel
Schattauer GmbH

Internal Mammarial Lymphoscintigraphy with SPECT after Ultrasound-Guided Injection of 99mTc-Dextran[*]

Interne Mammial Lymphoszintigraphie mit SPECT nach Ultraschall-Guided Injektion von 99mTc-Dextran
M. Ünlü
1   From the Departments of Nuclear Medicine, Ankara, Turkey
,
T.M. Ercan
1   From the Departments of Nuclear Medicine, Ankara, Turkey
,
H. Alanyali
2   From the Departments of Radiotherapy, Ankara, Turkey
,
O. Akhan
3   From the Departments of Radiology, Faculty of Medicine, Hacettepe University, Ankara, Turkey
,
F.C. Bekdik
1   From the Departments of Nuclear Medicine, Ankara, Turkey
› Author Affiliations
Further Information

Publication History

Received: 09 October 1989

in revised form: 24 November 1989

Publication Date:
04 February 2018 (online)

Also available at
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Twenty-two women with stage II or III breast cancer were evaluated by SPECT to determine the number, size, three-dimensional localization and depth from skin surface of the internal mammary lymph nodes for accurate radiotherapy portal planning. The results were also compared with those of planar imaging (PI). Two-step injections of 99mTc-dextran were made under ultrasound guidance into the anterior sheath of the M. rectus abdominis first at the ablation side. 1.5 h thereafter an anterior planar view was obtained to evaluate cross drainage (13.6% was observed). Then, the second injection was done at the opposite side in the same manner. Planar and tomographic images were obtained 1.5 h after the second injection. Similar values were obtained for the depth from skin surface, distance from the midline and diameter of the lymph nodes with both PI and SPECT. The total number of nodes in 22 patients detected by SPECT was higher (138) than that from PI (129), the difference being statistically significant (0.005 > p >0.0005).

Zusammenfassung

Um die Anzahl, Größe, dreidimensionale Lokalisation und Tiefe unter der Hautoberfläche parasternaler Lymphknoten zwecks exakter Planung der Radiotherapie eines Mamma-Karzinoms zu bestimmen, wurden 22 Frauen mit Mamma-Karzinom der Stadien II oder III mittels SPECT untersucht. Die Ergebnisse wurden mit jenen einer planaren Szintigraphie (PS) verglichen. 99mTc-Dextran wurde in zwei Stufen unter Ultraschall-Kontrolle in die vordere Scheide des M. rectus abdominis injiziert. Die erste erfolgte auf der Seite der Ablation; 1.5h später zeigte ein planares Bild die eventuelle Drainage zur anderen Seite (beobachtet bei 13,6% der Fälle). Die zweite Injektion erfolgte auf der anderen Seite; jetzt wurde nach 1.5h sowohl eine PS als auch eine SPECT durchgeführt. Beide Methoden ergaben ähnliche Werte für die Tiefe unter der Haut und die Größe der Lymphknoten sowie für ihren Abstand von der Mittellinie. Die Anzahl der diagnostizierten Knoten war jedoch bei der SPECT mit 138 höher als jene bei der PS (129), wobei diese Differenz signifikant war (0,005 >p >0,0005).

* This work was presented in part as a poster at the European Association of Nuclear Medicine Congress, Aug. 28-Sept. 1, 1989, Strasbourg, France.


 

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