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Nuklearmedizin 1991; 30(04): 149-150
DOI: 10.1055/s-0038-1629567
Fallberichte - Case Reports
Schattauer GmbH

99mTc-Labelled Anti NCA-95 Antibodies in Prosthetic Heart Valve Endocarditis

99mTc-markiertes Anti-NCA-95 Antikörper im prothetischen Herzen Klappenendokarditis
H.-J. Bair
1   From the Department of Nuclear Medicine, University of Erlangen-Nürnberg, Erlangen, FRG
,
W. Becker
1   From the Department of Nuclear Medicine, University of Erlangen-Nürnberg, Erlangen, FRG
,
H.-J. Volkholz
*   Department of internal Medicine I, University of Erlangen-Nürnberg, Erlangen, FRG
,
F. Wolf
1   From the Department of Nuclear Medicine, University of Erlangen-Nürnberg, Erlangen, FRG
› Author Affiliations
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Publication History

Received: 01 March 1991

Publication Date:
05 February 2018 (online)

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A 54-y old women with earlier replacement of the mitral and aortic valves and clinical signs of localized endocarditis was studied with 99mTc-labelled anti NCA-95 antibody. Whereas echocardiographic findings were negative, increased radionuclide uptake was observed left parasternal over the mitral valve as a sign of prosthetic valve endocarditis. This result could be confirmed by a similar study with leukocytes labelled in vitro with 111ln-oxine.

Zusammenfassung

Bei einer 54jährigen Patientin mit klinischen Zeichen der Sepsis bei bekanntem Ersatz der Mitral- und Aortenklappen konnte die Mitralklappe als Fokus mittels monoklonaler 99mTc-markierter Anti-NCA-95-Antikörper erkannt werden. Der Befund konnte durch die Verwendung von Leukozyten, die mit 111In-Oxin markiert waren, bestätigt werden.

 

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