A Quantitative Index Derived from 99mTc-Pertechnetate Scintigraphy to Assist in the Diagnosis of Primary Sjogren’s Syndrome

H. M. Markusse; M. Pillay; P. H. Cox

doi:10.1055/s-0038-1629592

Nuklearmedizin - NuclearMedicine, Inhaltsverzeichnis

Nuklearmedizin 1992; 31(01): 3-6
DOI: 10.1055/s-0038-1629592

Originalarbeiten

Schattauer GmbH

A Quantitative Index Derived from ^99mTc-Pertechnetate Scintigraphy to Assist in the Diagnosis of Primary Sjogren’s Syndrome

Ein von der ^99mTc-Pertechnetatszintigraphie abgeleiteter quantitativer Index zur Unterstützung bei der Diagnose des primären Sjögren-Syndroms

H. M. Markusse

¹From the Departments of Rheumatology and of Nuclear Medicine, Dr. Daniel den Hoed Clinic, Rotterdam, The Netherlands

,

M. Pillay

,

P. H. Cox

› Institutsangaben

Abstract

Zusammenfassung

Eine sichere und einfache szintigraphische Technik der Diagnose des primären Sjögren-Syndroms wird erläutert, die eine relativ hohe Spezifität und Sensitivität erbringt. Bisher wurde mit brauchbarem Erfolg die Serienszintigraphie eingesetzt; die hier beschriebene Verwendung des Linearitäts-Index erbrachte jedoch bessere Ergebnisse. Bei 71 untersuchten Patienten wurde eine Sensitivität von 87% und eine Spezifität von 93% ermittelt. Somit ist dies die Methode der Wahl zur Bewertung von Patienten mit Verdacht auf primäres Sjögren-Syndrom.

Summary

A safe and simple technique is reported by which primary Sjogren’s syndrome can be detected with a relatively high specificity and sensitivity. The method of serial scintigraphy has been used with reasonable success; however, the application of the linearity index as described here produced superior results. In 71 patients investigated, a sensitivity of 87% and specificity of 93% were recorded and make this the method of choice for evaluating patients suspected of having primary Sjogren’s syndrome.

Schlüsselwörter

^99mTc-pertechnetat - Primäres Sjögren-Syndrom - Linearitäts-Index - Rheumatologie - Speicheldrüsenfunktion

Key words

⁹⁹mTc-pertechnetate - primary Sjögren’s syndrome - linearity index - rheumatology - salivary gland function

Volltext

Referenzen

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