Criteria and Quantification of Fibrous Dysplasia on MDP Scanning

Summary

Eleven patients with histologically proven fibrous dysplasia (biopsy) were imaged with 3-phase bone scanning, using ^99mTc-MDP. Ten had monostotic and one had polyostotic fibrous dysplasia. The perfusion (phase I) and uptake (phase III) of monostotic lesions was compared to the normal contralateral side and the rest of the skeleton was inspected for other abnormalities. Lesions presented with slightly increased perfusion (1.65 normal ± 0.907) and markedly increased uptake of tracer (6.0 normal ± 2.58). Other features that were noted are high spinal and scapula and poor renal tracer uptake.

Zusammenfassung

Elf Patienten mit histologisch (Biopsie) nachgewiesener fibröser Dysplasie wurden mittels ^99mTc-MDP und Dreiphasen-Knochenszintigraphie untersucht. Zehn litten an der monostotischen und einer an der polyostotischen Form. Die Perfusion (Phase I) und der Uptake (Phase III) der monostotischen Läsionen wurden mit der gesunden kontralateralen Seite verglichen und das übrige Skelett auf andere Veränderungen untersucht. Die Läsionen zeigten eine leicht erhöhte Perfusion (1,65 normal ± 0,907) und einen deutlich erhöhten Uptake (6,0 normal ± 2,58). Ferner wurden eine hohe Speicherung in der Wirbelsäule und den Schulterblättern und eine nur geringe Speicherung in den Nieren festgestellt.

Keywords

Fibrous dysplasia - nuclear medicine - ^99mTc-MDP

Schlüsselwörter

Fibröse Dysplasie - Nuklearmedizin - ^99mTc-MDP

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