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Vet Comp Orthop Traumatol 2001; 14(01): 32-39
DOI: 10.1055/s-0038-1632670
DOI: 10.1055/s-0038-1632670
Clinical Communications
An ovine model for total hip replacement: operative procedure and complications
Weitere Informationen
Publikationsverlauf
Received
01. November 1999
Accepted
20. April 2000
Publikationsdatum:
09. Februar 2018 (online)
Summary
A cranio-lateral curvilinear incision in the skin was centered over the greater trochanter. The subsequent approach to the acetabulum involved blunt dissection and avoided the need for significant muscular incision. The major post-operative complications encountered were fracturing of the proximal (2/37) and distal femur (4/37), caudal neuropathy (2/37) and septic femoral stem loosening (1/37). At two years post-operatively, the morbidity rate was 24% and the mortality rate 19%.
A regime of analgesia, involving constant infusion of xylazine, was developed and appeared very effective.
Thirty-seven mature Merino wethers were utilized for an evaluation of a new acetabular cup design using a modular cemented total hip replacement system. The ovine model for total hip replacement provided a reliable and manageable method for the evaluation of component design and tissue response.
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REFERENCES
- 1 Howie DW, Middleton RG, Costi K. Loosening of matt and polished cemented femoral stems. J Bone Joint Surg (Br) 1998; 80-B: 573-6.
- 2 Anthony PP, Gie GA, Howie CR, Ling RS. Localised endosteal bone lysis in relation to the femoral components of cemented total hip arthroplasties. J Bone Joint Surg (Br) 1990; 72: 971-9.
- 3 Pritchett JW. Femoral bone loss following hip replacement. A comparative study. Clin Orthop 1995; 314: 156-61.
- 4 Maloney WJ, Jasty M, Burke DW, O’Connor DO, Zalenski EB, Bragdon C, Harris WH. Biomechanical and histologic investigation of cemented total hip arthroplasties. Clin Orthop 1989; 249: 129-40.
- 5 Howie DW, Vernon-Roberts B. Synovial macrophage response to aluminum oxide and cobalt-chrome alloy wear particles in rats. Biomaterials 1988; 09: 442-8.
- 6 Howie DW, Vernon-Roberts B. Long-term effects of intra-articular cobalt-chrome allow wear particles in rats. J Arthroplasty 1988; 03: 327-36.
- 7 Jasty M, Maloney WJ, Bragdon CR, O’Connor DO, Haire T, Harris WH. The initiation of failure in cemented femoral components of hip arthroplasties. J Bone Joint Surg (Br) 1991; 73: 551-8.
- 8 Olmstead ML, Hohn RB, Turner TM. A five year study of 221 total hip replacements in the dog. J Am Vet Med Assoc 1983; 183: 191-4.
- 9 Montgomery RD, Milton JL, Pernell R, Aberman HM. Total hip arthroplasty for treatment of canine hip dysplasia. Vet Clin Nth Amer 1992; 22: 703-19.
- 10 Sumner DR, Turner TM, Urban RM, Galante JO. Remodeling and ingrowth of bone at two years in a canine cementless total hip-arthroplasty model. J Bone Joint Surg (Am) 1989; 74: 239-50.
- 11 Bruns DP, Olmstead ML, Litsky AS. Technique and results for total hip replacement in sheep: An experimental model. Vet Comp Orthop Traumatol 1996; 09: 158-64.
- 12 Rasmir-Raven AM, DeYoung DJ, Abrams CF, Aberman HA, Richardson DC. Subsidence of an uncemented canine femoral stem. Vet Surg 1992; 21: 327-31.
- 13 DeYoung DJ, De Young BA, Aberman HA, Kenna RV, Hungerford DS. Implantation of an uncemented total hip prosthesis. Technique and initial results of 100 arthroplasties. Vet Surg 1992; 21: 168-77.
- 14 Brumby SA, Howie DW, Pearcy MJ, Wang AW, Nawana NS. Radiographic and histologic analysis of cemented double-tapered femoral stems. Clin Orthop 1998; 355: 229-37.
- 15 Newman E, Turner AS, Wark JD. The potential of sheep for the study of osteopenia: current status and comparison with other animal models. Bone 1995; 16: 277S-84S.
- 16 Turner AS, Eckhoff DG, Dewell RD. Peri-apatite coated implants improve fixation in osteopenic bone. New Orleans, Louisianna: 44th Ann Meeting Orthop Res Soc. 1998
- 17 Middleton RG, Reilly DT, Jessop J. Occlusion of the external iliac vein by cement. J Arthroplasty 1996; 11: 346-7.
- 18 Ratcliff AHC. Vascular and neurological complications. In: Complications of total hip replacement. Ling RSM. (ed). New York: Churchill Livingston; 1984: 18.
- 19 Wagner AE. Analgesic management of animals used in orthopedic research. Proc. Orthopedic Animal Models. Virginia: Arlington; 1999
- 20 Grant C, Upton RN, Kuchel TR. Efficacy of intra-articular analgesis for acute pain in sheep. Aust Vet 1996; J 73: 129-32.
- 21 Scherr DD, Dodd TA, Buckingham WW. Prophylactic use of topical antibiotic irrigation in uninfected surgical wounds. J Bone Joint Surg (Am) 1972; 54: 634-40.
- 22 Lineweaver W, Howard R, Soucy D. et al. Topical antimicrobial toxicity. Arch Surg 1985; 120: 267-70.
- 23 Wang AW. Femoral bone remodelling following cemented hip arthroplasty in a sheep model. PhD Thesis, University of Adelaide. 1998: 52-62.
- 24 Radin EL, Rubin CT, Thrasher EL. et al. Changes in the bone-cement interface after total hip replacement. J Bone Jt Surg (Am) 1982; 64-A: 1188-200.
- 25 Waterman AE, Livingston A, Amin A. Further studies on the antinocioceptive activity and respiratory effects of buprenorphine in sheep. J Vet Pharmacol Ther 1991; 14: 230-4.
- 26 Chambers JP, Waterman AE, Livingston A. The effects of opiod and alpha 2 adrenergic blockade on non-steroidal anti-inflammatory drug analgesia in sheep. J Vet Pharmacol Ther 1995; 18: 161-6.
- 27 Nolan A, Livingston A, Waterman AE. Antinociopceptive actions of intravenous alpha 2-adrenoceptor agonists in sheep. J Vet Pharmacol Ther 1987; 10: 202-9.