Download PDF
Vet Comp Orthop Traumatol 2005; 18(01): 52-54
DOI: 10.1055/s-0038-1632929
Case Report
Schattauer GmbH

Bioartificial bone grafting:Tarsal joint fusion in a dog using a bioartificial composite bone graft consisting of β-tricalciumphosphate and platelet rich plasma – A case report

G. Hauschild
1   Department of Thorax-, Heart- and Vessel-Surgery, Hannover Medical School, Hannover, Germany
2   Small Animal Clinic, Hannover Veterinary Medical School, Hannover, Germany
,
H.-A. Merten
3   Department of Oral- and Maxillofacial Surgery, University of Göttingen, Göttingen, Germany
,
A. Bader
4   Section for Tissue Engineering, Department of Anatomy, Eberhard-Karls-University Tübingen, Tübingen, Germany
,
G. Uhr
5   Department of Zoology, Hannover Veterinary Medical School, Hannover, Germany
,
A. Deivick
6   Gesellschaft für Biotechnologische Forschung, Braunschweig, Germany
,
A. Meyer-Lindenberg
2   Small Animal Clinic, Hannover Veterinary Medical School, Hannover, Germany
,
M. Fehr
1   Department of Thorax-, Heart- and Vessel-Surgery, Hannover Medical School, Hannover, Germany
› Author Affiliations
Further Information

Publication History

Received 12 August 2003

Accepted 05 July 2004

Publication Date:
08 February 2018 (online)

Also available at
    Permissions and Reprints

Summary

Grafting of large bone defects caused by trauma or tumor resection still remains a problem to solve. In experimental studies as well as in human dentistry, osteoconduction and biodegradation of the β-tricalciumphosphate Cerasorb® as well as osteoinductive capabilities of platelet rich plasma have been proven. In case of luxation of the right tarsal joint, including a compressive fracture of the forth tarsal bone, the recommended use of autologous cancellous bone to support osseous fusion was replaced by the use of a bioartificial bone graft. Biodegradation of the bone graft was proven clinically and radiographically. Complete osseous fusion of the intertarsal joint occurred. The use of the β-tricalciumphosphate Cerasorb in combination with platelet rich plasma to support a partial arthrodesis of the tarsal joint in a dog did not impede the healing process but led to full recovery of the patient, indicating that this concept of bioartificial bone grafting could support bone healing.

Keywords

Bonegraft - β-tricalciumphosphate
 

  • References

  • 1 Sakar M, Bakker FC, Stahl JP, Schnettler R. Biobonein Calciumphosphat-Zement zur Auffüllung knöcherner Defekte. Ergebnisse der klinischen Pilotstudie mit 49 Patienten. Unfallchirurg 1999; 275: 238-9.
    PubMedSearch in Google Scholar
  • 2 Foitzik C, Stam M. Einsatz von phasenreinem ß-Tricalciumphosphat zur Auffüllung von ossären Defekten-Biologische Materialvorteile und klinische Erfahrungen. Quintessenz 1997; 48: 1365-77.
    PubMedSearch in Google Scholar
  • 3 Heide H, Karbe E, Kling HG, König R, Köster K, Kramer H. Entwicklung und tierexperimentelle Untersuchungen von implantierbaren, porösen keramischen Werkstoffen. Zwei Teilberichte für das Bundesministerium für Forschung und Technologie. Bonn, Referat III B 3,7 / 12 1973
    PubMedSearch in Google Scholar
  • 4 Foitzik C, Staus H. Phasenreines ß-Tricalciumphosphat zum Knochenersatz bei parodontaler Indikation. Quintessenz 199 10: 1049-58.
    PubMed
  • 5 Marx RE, Carlson ER, Eichstaedt RM, Schimmerle SR, Strauss JE, Georgeff KR. Platelet-rich plasma – Growth factor enhancement for bone grafts. Oral Sur Oral Med Oral Pathol Oral Radiol Endod 1998; 85: 638-46.
    PubMedSearch in Google Scholar