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DOI: 10.1055/s-0038-1633956
Libraries of Strategies and Ontology-driven Subject Area Models as “Corner Stones” in Grid Development
Publication History
Publication Date:
05 February 2018 (online)
![](https://www.thieme-connect.de/media/10.1055-s-00035037/200502/lookinside/thumbnails/10-1055-s-0038-1633956-1.jpg)
Summary
Series of experiments of Grid-based calculations by Monte-Carlo simulation of molecular conformations have shown that there are classes of problems that could be “gridified” in short time with reasonable efforts. That could awake serious interest in the Grid from the biophysics and biochemistry community. Experiments with scientific problems that include both intensive computations and intensive data interchange have shown that libraries of strategies could provide an effective tool to adapt Grid-node infrastructure to problem structure. Libraries of strategies on different levels of Grid hierarchy – from local clusters to regional segments – could provide an effective usage of Grid resources.
Ontologies provide a universal tool to link distributed databases. Besides, ontologies also allow for the formal construction of models of subject areas. These models are the tools to formalize information requests and to construct intellectual queries to information space. There should be a multi-level hierarchy of ontologies and a critical mass of low-level ontologies must be reached in order to build a knowledge space for a subject area.
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References
- 1 Khvostunov IK, Andreev SG, Eidelman YA. Biophysical Analysis of Radiation Induced Initial DNA Fragmentation/Radiation Protection Dosimetry. Nuclear Technology Publishing 2002; 99 1-4 151-2.