Elaboration and Formalization of Current Scientific Knowledge of Risks and Preventive Measures Illustrated by Colorectal Cancer

R. Giorgi; J. Gouvernet; J. Dufour; P. Degoulet; R. Laugier; F. Quilichini; M. Fieschi

doi:10.1055/s-0038-1634428

Methods of Information in Medicine, Table of Contents

Methods Inf Med 2001; 40(04): 323-330
DOI: 10.1055/s-0038-1634428

Original Article

Schattauer GmbH

Elaboration and Formalization of Current Scientific Knowledge of Risks and Preventive Measures Illustrated by Colorectal Cancer

R. Giorgi

¹Laboratoire d’Enseignement et de Recherche sur le Traitement de l’Information Médicale (LERTIM), Faculté de Médecine, Université de la Méditerranée, Marseille, France

,

J. Gouvernet

¹Laboratoire d’Enseignement et de Recherche sur le Traitement de l’Information Médicale (LERTIM), Faculté de Médecine, Université de la Méditerranée, Marseille, France

,

J. Dufour

¹Laboratoire d’Enseignement et de Recherche sur le Traitement de l’Information Médicale (LERTIM), Faculté de Médecine, Université de la Méditerranée, Marseille, France

,

P. Degoulet

²Santé Publique et Informatique Médicale (SPIM), Faculté de Médecine Broussais-Hôtel-Dieu, Paris, France

,

R. Laugier

³Service de Gastroentérologie,Marseille, France

,

F. Quilichini

⁴Service de Chirurgie Générale et Digestive, Centre Hospitalier Universitaire de Marseille, Hôpital d’Adultes de la Timone, Marseille, France

,

M. Fieschi

¹Laboratoire d’Enseignement et de Recherche sur le Traitement de l’Information Médicale (LERTIM), Faculté de Médecine, Université de la Méditerranée, Marseille, France

› Author Affiliations

Abstract

Summary

Objectives: Present the method used to elaborate and formalize current scientific knowledge to provide physicians with tools available on the Internet, that enable them to evaluate individual patient risk, give personalized preventive recommendations or early screening measures.

Methods: The approach suggested in this article is in line with medical procedures based on levels of evidence (Evidence-based Medicine). A cyclical process for developing recommendations allows us to quickly incorporate current scientific information. At each phase, the analysis is reevaluated by experts in the field collaborating on the project. The information is formalized through the use of levels of evidence and grades of recommendations. GLIF model is used to implement recommendations for clinical practice guidelines.

Results: The most current scientific evidence incorporated in a cyclical process includes several steps: critical analysis according to the Evidence-based Medicine method; identification of predictive factors; setting-up of risk levels; identification of prevention measures; elaboration of personalized recommendation. The information technology implementation of the clinical practice guideline enables physicians to quickly obtain personalized information for their patients. Cases of colorectal prevention illustrate our approach.

Conclusions: Integration of current scientific knowledge is an important process. The delay between the moment new information arrives and the moment the practitioner applies it, is thus reduced.

Keywords

Evidence-based Medicine - Practice Guidelines - Primary Prevention - Mass Screening - Colorectal Neoplasm

Full Text

References

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