Modeling Drug Information for a Prescription – Oriented Knowledge Base on Drugs

Abstract:

There exists little theoretical analysis how to represent knowledge on drugs required for computerized drug-prescription applications. A work package drug information modeling is described which was part of the European GPADE project. We describe the content and structure of a Drug Knowledge Base (DKB) designed to meet the requirements of decision-support systems in the domain of drug therapy, and to facilitate data transfer from various information sources. The definition of the DKB content is derived from the analysis of information requirements at the various stages of the process of the clinical usage of drugs (prescribing, administration, and follow-up). The DKB structure results from the classification of the various data items along two dimensions: (1) entities in the pharmaco-therapeutic domain for which information must be defined (the Pharmaco-Therapeutic Group, the Component, the Manufactured Preparation, and the Presentation), and (2) the validity score of the pharmaco-therapeutic information (international, national, or local).

Keywords:

Drug Prescription - Knowledge Base - Information Modeling

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