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Methods Inf Med 1985; 24(02): 91-100
DOI: 10.1055/s-0038-1635359
Original Article
Schattauer GmbH

Analysis of Maximum Expiratory Flow Volume Curves Using Canonical Correlation Analysis[*]

Analyse der maximalen exspiratorischen Fluß-Volumen-Kurve mittels der kanonischen Korrelationsanalyse
W. van Pelt
1   (From the Departments of Physiology and Physiological Physics and of Data Theory, the University of Leiden, and the Department of Epidemiology, the University of Groningen, The Netherlands)
,
Ph. H. Quanjer
1   (From the Departments of Physiology and Physiological Physics and of Data Theory, the University of Leiden, and the Department of Epidemiology, the University of Groningen, The Netherlands)
,
M. E. Wise
1   (From the Departments of Physiology and Physiological Physics and of Data Theory, the University of Leiden, and the Department of Epidemiology, the University of Groningen, The Netherlands)
,
E. van der Burg
1   (From the Departments of Physiology and Physiological Physics and of Data Theory, the University of Leiden, and the Department of Epidemiology, the University of Groningen, The Netherlands)
,
R. van der Lende
1   (From the Departments of Physiology and Physiological Physics and of Data Theory, the University of Leiden, and the Department of Epidemiology, the University of Groningen, The Netherlands)
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Publikationsverlauf

Publikationsdatum:
20. Februar 2018 (online)

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Summary

As part of a population study on chronic lung disease in the Netherlands, an investigation is made of the relationship of both age and sex with indices describing the maximum expiratory flow-volume (MEFV) curve. To determine the relationship, non-linear canonical correlation was used as realized in the computer program CANALS, a combination of ordinary canonical correlation analysis (CCA) and non-linear transformations of the variables. This method enhances the generality of the relationship to be found and has the advantage of showing the relative importance of categories or ranges within a variable with respect to that relationship. The above is exemplified by describing the relationship of age and sex with variables concerning respiratory symptoms and smoking habits. The analysis of age and sex with MEFV curve indices shows that non-linear canonical correlation analysis is an efficient tool in analysing size and shape of the MEFV curve and can be used to derive parameters concerning the whole curve.

Als Teil einer Bevölkerungsstudie über chronische Lungenkrankheiten in den Niederlanden wird die Beziehung zwischen Alter und Geschlecht einerseits und den die Kurve des maximalen exspiratorischen Fluß-Volumens (MEFV) beschreibenden Meßwerten andererseits untersucht.

Zur Bestimmung dieser Beziehung wurde die nichtlineare kanonische Korrelation verwendet, wie sie im Computerprogramm CANALS vorliegt: Eine Kombination der gewöhnlichen kanonischen Korrelationsanalyse (CCA) mit nichtlinearen Transformationen der Variablen. Diese Methode erhöht die Allgemeingültigkeit der festzustellenden Beziehung und hat den Vorteil, die relative Bedeutung von Kategorien oder Rängen innerhalb einer Variablen hinsichtlich dieser Beziehung aufzuzeigen.

Die obige Methode wird zur Beschreibung der Beziehungen zwischen Alter und Geschlecht einerseits und den die Atmungssymptome und Rauchgewohnheiten betreffenden Variablen andererseits angewandt. Die Analyse von Alter und Geschlecht mit den MEFV-Kurvenmeß-werten zeigt, daß die nichtlineare kanonische Korrelationsanalyse ein wirksames Werkzeug zur Analyse der Größe und Form der MEFV-Kurve darstellt und zur Ableitung von Parametern in bezug auf die gesamte Kurve benutzt werden kann.

Key-Words:

MEFV Curve - Curve Analysis - Canonical Correlation Analysis - Non-linear Transformations

Schlüssel-Wörter:

MEFV-Kurve - Kurvenanalyse - kanonische Korrelationsanalyse - nichtlineare Transformationen

* Requests for reprints: W. van Pelt, Physiology Laboratory, P. O. Box 9604, 2300 RC Leiden, The Netherlands


 

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