Endoscopy 2018; 50(04): S157
DOI: 10.1055/s-0038-1637507
ESGE Days 2018 ePosters
Georg Thieme Verlag KG Stuttgart · New York

PATTERN OF ENDOSCOPIC FINDINGS IN PATIENTS WITH UNINVESTIGATED DYSPEPSIA IN EGYPT

M Aboelmagd
1   Suez Canal University, Endemic and Infectious Diseases, Ismailia, Egypt
,
F Rageh
1   Suez Canal University, Endemic and Infectious Diseases, Ismailia, Egypt
,
M Elhamouly
1   Suez Canal University, Endemic and Infectious Diseases, Ismailia, Egypt
› Author Affiliations
Further Information

Publication History

Publication Date:
27 March 2018 (online)

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Aims:

To investigate the endoscopic findings and predicators of organic dyspepsia in patients with uninvestigated dyspepsia.

Methods:

Over a period of 25 months (2015 – 2017), 375 adult outpatients (median age 43 years, range 17 – 85; 165 male; 210 female) were referred for upper gastrointestinal endoscopy because of uninvestigated dyspepsia. The patient's medical history was recorded and biopsies were taken from all patients for the histological diagnosis of H. pylori and diagnosis of any suspected lesions.

Results:

Out of the 375 patients studied, 68.3% (n = 256) were H. pylori positive, 45.6% (n = 171) were younger than 40 years. The prevalence of peptic ulcer was 9.3% (n = 35), duodenal ulcer 7.5% (n = 28), adenocarcinoma 3.2% (n = 12) and MALT 1.9% (n = 7). The cutoff value for age as indication for endoscopy was 40 years which associated with organic dyspepsia with sensitivity 60.68% and specificity 68.75% (AUROC = 0.624, P value = 0.001). In multivariate analysis, Age > 40 years (OR: 2.62 95% CI 1.38 – 4.96), GI bleeding (OR: 2.43 95% CI 1.04 – 5.67) and positive H. Pylori (OR: 21.22 95% CI 10.77 – 41.84) were significantly predicators for organic dyspepsia

Conclusions:

Age, GI bleeding and positive H. Pylori are valuable factors in predicating organic dyspepsia in Egyptian patients with uninvestigated dyspepsia and can be used as indication for endoscopy to avoid unnecessary procedures.