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DOI: 10.1055/s-0038-1638536
Care Provider Order Entry (CPOE): A Perspective on Factors Leading to Success or to Failure
The authors would like to thank Antoine Geissbuhler, William Stead, Doug Talbert, Russ Waitman, and many others for their substantial contributions to Vanderbilt’s CPOE system. Dr. Miller’s work has been supported in part by a grant from the U.S. National Library of Medicine, R01-LM-007995.Publication History
Publication Date:
05 March 2018 (online)
Summary
Objective
Authors provide a perspective on factors leading to successful care provider order entry (CPOE) implementations.
Methods
Viewpoint of authors supported by background literature review.
Results
Authors review both benefits and challenges related to CPOE implementation using three guiding principles: (1) a clinical approach to clinical systems, which claims that CPOE implementation is analogous to a “good” clinician delivering care to a patient; (2) a commitment to quality, which advocates that no compromises should be made in implementing system functionality and clinical system content – the highest objective for CPOE implementation is to provide better quality of care and increased safety for patients; (3) a commitment to fairness, as evidenced by respect for individuals and support of local autonomy, which advocates for minimizing disruptions to clinician-users’ workflows, and adequate local control over CPOE system design and evolution, including clinical content management.
Conclusions
Past experiences with CPOE implementation can inform future installation attempts. Sociocultural factors dominate in determining the success of implementation, and should govern technical factors.
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References
- 1 Kohn LT, Corrigan JM, Donaldson MS. To Err is Human: Building a Safer Health System. Washington D.C: National Academy Press; 2000
- 2 Crossing the Quality Chasm: A New Health System for the 21st Century. Washington D.C: National Academy Press; 2001
- 3 The Leapfrog Group for Patient Safety: Rewarding Higher Standards. www.leapfroggroup.org (accessed 04-14-2007)
- 4 Mekhjian HS, Kumar RR, Kuehn L, Bentley TD, Teater P, Thomas A. et al. Immediate benefits realized following implementation of physician order entry at an academic medical center. J Am Med Inform Assoc 2002; 09 (05) 529-39.
- 5 Westbrook JI, Georgiou A, Dimos A, Germanos T. Computerised pathology test order entry reduces laboratory turnaround times and influences tests ordered by hospital clinicians: a controlled before and after study. J Clin Pathol 2006; 59 (05) 533-6.
- 6 Cordero L, Kuehn L, Kumar RR, Mekhjian HS. Impact of computerized physician order entry on clinical practice in a newborn intensive care unit. J Perinatol 2004; 24 (02) 88-93.
- 7 Ash JS, Gorman PN, Seshadri V, Hersh WR. Computerized physician order entry in U.S. hospitals: results of a 2002 survey. J Am Med Inform Assoc 2004; 11 (02) 95-9.
- 8 Campbell EM, Sittig DF, Ash JS, Guappone KP, Dykstra RH. Types of unintended consequences related to computerized provider order entry. J Am Med Inform Assoc 2006; 13 (05) 547-56.
- 9 Massaro TA. Introducing physician order entry at a major academic medical center: II. Impact on medical education. Acad Med 1993; 68 (01) 25-30.
- 10 Massaro TA. Introducing physician order entry at a major academic medical center: I. Impact on organizational culture and behavior. Acad Med 1993; 68 (01) 20-5.
- 11 Wang CJ, Marken RS, Meili RC, Straus JB, Landman AB, Bell DS. Functional characteristics of commercial ambulatory electronic prescribing systems: a field study. J Am Med Inform Assoc 2005; 12 (03) 346-56.
- 12 American Hospital Association. AHA Guide to Computerized Order Entry Applications. Washington D.C: American Hospital Association; 2000
- 13 Miller RA, Waitman LR, Chen S, Rosenbloom ST. The anatomy of decision support during inpatient care provider order entry (CPOE): Empirical observations from a decade of CPOE experience at Vanderbilt. J Biomed Inform 2005; 38 (06) 469-85.
- 14 Sittig DF, Stead WW. Computer-based physician order entry: the state of the art. J Am Med Inform Assoc 1994; 01 (02) 108-23.
- 15 Bates DW. Computerized physician order entry and medication errors: Finding a balance. J Biomed Inform 2005; 38 (04) 259-61.
- 16 McDonald CJ, Overhage JM, Tierney WM, Dexter PR, Martin DK, Suico JG. et al. The Regenstrief Medical Record System: a quarter century experience. Int J Med Inform 1999; 54 (03) 225-53.
- 17 Teich JM, Glaser JP, Beckley RF, Aranow M, Bates DW, Kuperman GJ. et al. The Brigham integrated computing system (BICS): advanced clinical systems in an academic hospital environment. Int J Med Inform 1999; 54 (03) 197-208.
- 18 Gardner RM, Pryor TA, Warner HR. The HELP hospital information system: update 1998. Int J Med Inform 1999; 54 (03) 169-82.
- 19 Brown SH, Lincoln MJ, Groen PJ, Kolodner RM. VistA-U.S. Department of Veterans ffairs nationalscale HIS. Int J Med Inform 2003; 69 (2-3): 135-56.
- 20 Dexter PR, Perkins S, Overhage JM, Maharry K, Kohler RB, McDonald CJ. A computerized reminder system to increase the use of preventive care for hospitalized patients. N Engl J Med 2001; 345 (13) 965-70.
- 21 Overhage JM, Tierney WM, Zhou XH, McDonald CJ. A randomized trial of “corollary orders” to prevent errors of omission. J Am Med Inform Assoc 1997; 04 (05) 364-75.
- 22 Evans RS, Pestotnik SL, Classen DC, Clemmer TP, Weaver LK, Orme Jr JF, Lloyd JF. et al. A computer-assisted management program for antibiotics and other antiinfective agents. N Engl J Med 1998; 338 (04) 232-8.
- 23 Bates DW, Teich JM, Lee J, Seger D, Kuperman GJ, Ma’Luf N. et al. The Impact of Computerized Physician Order Entry on Medication Error Prevention. J Am Med Inform Assoc 1999; 06 (04) 313-21.
- 24 Bates DW, Leape LL, Cullen DJ, Laird N, Petersen LA, Teich JM, Burdick E. et al. Effect of computerized physician order entry and a team intervention on prevention of serious medication errors. Jama 1998; 280 (15) 1311-6.
- 25 Borst F, Appel R, Baud R, Ligier Y, Scherrer JR. Happy birthday DIOGENE: a hospital information system born 20 years ago. Int J Med Inform 1999; 54 (03) 157-67.
- 26 Scherrer JR. The integrated real-time hospital information system: DIOGENE. World Hosp 1983; 19 (04) 8-11.
- 27 Scherrer JR, Baud RH, Hochstrasser D, Ratib O. An integrated hospital information system in Geneva. MD Comput 1990; 07 (02) 81-9.
- 28 Peterson HE. From punched cards to computerized patient records: a personal journey. Methods Inf Med 2006; 45 (Suppl. 01) 180-6.
- 29 Sjoborg B, Backstrom T, Arvidsson LB, Andersen Earlsson, Blomberg LB, Eiermann B. et al. Design and implementation of a point-of-care computerized system for drug therapy in Stockholm metropolitan health region-Bridging the gap between knowledge and practice. Int J Med Inform 2007; Jul; 76 (07) 497-506.
- 30 Bakker AR, Leguit FA. Evolution of an integrated HIS in The Netherlands. Int J Med Inform 1999; 54 (03) 209-24.
- 31 Kalmeijer MD, Holtzer W, van Dongen R, Guchelaar HJ. Implementation of a computerized physician medication order entry system at the Academic Medical Centre in Amsterdam. Pharm World Sci 2003; 25 (03) 88-93.
- 32 Boon WM, Westerhof HP, Duisterhout JS, Cromme PV. The role of AIDA in a primary care information system. Comput Methods Programs Biomed 1987; 25 (03) 287-96.
- 33 van der Lei J, Duisterhout JS, Westerhof HP, van der Does E, Cromme PV, Boon WM. et al. The introduction of computer-based patient records in The Netherlands. Ann Intern Med 1993; 119 (10) 1036-41.
- 34 Poley MJ, Edelenbos KI, Mosseveld M, van Wijk MA, de Bakker DH, van der Lei J. et al. Cost consequences of implementing an electronic decision support system for ordering laboratory tests in primary care: evidence from a controlled prospective study in the Netherlands. Clin Chem 2007; 53 (02) 213-9.
- 35 van Wijk MA, van der Lei J, Mosseveld M, Bohnen AM, van Bemmel JH. Assessment of decision support for blood test ordering in primary care. a randomized trial. Ann Intern Med 2001; 134 (04) 274-81.
- 36 Kuilboer MM, van Wijk MA, Mosseveld M, van der Does E, de Jongste JC, Overbeek SE. et al. Computed critiquing integrated into daily clinical practice affects physicians’ behavior—a randomized clinical trial with AsthmaCritic. Methods Inf Med 2006; 45 (04) 447-54.
- 37 Ogura H, Yamamoto K, Furutani H, Kitazoe Y, Hirakawa M, Sagara E. On-line prescription order and prescription support in an integrated hospital information system. Med Inform (Lond) 1985; 10 (04) 287-99.
- 38 Ogura H, Sagara E, Yamamoto K, Furutani H, Kitazoe Y, Takeda Y. Analysis of the online order entry process in an integrated hospital information system. Comput Biol Med 1985; 15 (06) 381-93.
- 39 Ogura H, Sagara E, Iwata M, Nishioka Y, Furutani H, Yamamoto K, Kitazoe Y. Online support functions of prescription order system and prescription audit in an integrated hospital information system. Med Inform (Lond) 1988; 13 (03) 161-9.
- 40 Hasman A, Safran C, Takeda H. Quality of health care: informatics foundations. Methods Inf Med 2003; 42 (05) 509-18.
- 41 Haruki Y, Ogushi Y, Okada Y, Kimura M, Kumamoto I, Sekita Y. Status and perspective of hospital information systems in Japan. Methods Inf Med 1999; 38 (03) 200-6.
- 42 Matsumura Y, Takeda H, Inoue M. Implementation of the totally integrated hospital information system (Humane) in Osaka University Hospital. Medinfo 1995; 08 Pt 1: 590-3.
- 43 Park RW, Shin SS, Choi YI, Ahn JO, Hwang SC. Computerized physician order entry and electronic medical record systems in Korean teaching and general hospitals: results of a 2004 survey. J Am Med Inform Assoc 2005; 12 (06) 642-7.
- 44 Hwang JI, Park HA, Bakken S. Impact of a physician’s order entry (POE) system on physicians’ ordering patterns and patient length of stay. Int J Med Inform 2002; 65 (03) 213-23.
- 45 Park WS, Kim JS, Chae YM, Yu SH, Kim CY, Kim SA. et al. Does the physician order-entry system increase the revenue of a general hospital?. Int J Med Inform 2003; 71 (01) 25-32.
- 46 Thompson W, Dodek PM, Norena M, Dodek J. Computerized physician order entry of diagnostic tests in an intensive care unit is associated with improved timeliness of service. Crit Care Med 2004; 32 (06) 1306-9.
- 47 Kuperman GJ, Gibson RF. Computer physician order entry: benefits, costs, and issues. Ann Intern Med 2003; 139 (01) 31-9.
- 48 Ozdas A, Speroff T, Waitman LR, Ozbolt J, Butler J, Miller RA. Integrating “best of care” protocols into clinicians’ workflow via care provider order entry: impact on quality-of-care indicators for acute myocardial infarction. J Am Med Inform Assoc 2006; 13 (02) 188-96.
- 49 Teich JM, Merchia PR, Schmiz JL, Kuperman GJ, Spurr CD, Bates DW. Effects of computerized physician order entry on prescribing practices. Arch Intern Med 2000; 160 (18) 2741-7.
- 50 Kucher N, Koo S, Quiroz R, Cooper JM, Paterno MD, Soukonnikov B. et al. Electronic alerts to prevent venous thromboembolism among hospitalized patients. N Engl J Med 2005; 352 (10) 969-77.
- 51 Shojania KG, Yokoe D, Platt R, Fiskio J, Ma’luf N, Bates DW. Reducing vancomycin use utilizing a computer guideline: results of a randomized controlled trial. J Am Med Inform Assoc 1998; 05 (06) 554-62.
- 52 Jha AK, Kuperman GJ, Teich JM, Leape L, Shea B, Rittenberg E. et al. Identifying Adverse Drug Events: Development of a Computer-based Monitor and Comparison with Chart Review and Stimulated Voluntary Report. J Am Med Inform Assoc 1998; 05 (03) 305-14.
- 53 Neilson EG, Johnson KB, Rosenbloom ST, Dupont WD, Talbert D, Giuse DA. et al. The impact of peer management on test-ordering behavior. Ann Intern Med 2004; 141 (03) 196-204.
- 54 Tierney WM, Miller ME, McDonald CJ. The effect on test ordering of informing physicians of the charges for outpatient diagnostic tests. N Engl J Med 1990; 322 (21) 1499-504.
- 55 Bates DW, Kuperman GJ, Jha A, Teich JM, Orav EJ, Ma’luf N. et al. Does the computerized display of charges affect inpatient ancillary test utilization?. Arch Intern Med 1997; 157 (21) 2501-8.
- 56 Bates DW, Kuperman GJ, Rittenberg E, Teich JM, Fiskio J, Ma’luf N. et al. A randomized trial of a computer-based intervention to reduce utilization of redundant laboratory tests. Am J Med 1999; 106 (02) 144-50.
- 57 Tierney WM, McDonald CJ, Martin DK, Rogers MP. Computerized display of past test results. Effect on outpatient testing. Ann Intern Med 1987; 107 (04) 569-74.
- 58 Tierney WM, McDonald CJ, Hui SL, Martin DK. Computer predictions of abnormal test results. Effects on outpatient testing. Jama 1988; 259 (08) 1194-8.
- 59 Sanders DL, Miller RA. The effects on clinician ordering patterns of a computerized decision support system for neuroradiology imaging studies. Proc AMIA Symp 2001; 583-7.
- 60 Harpole LH, Khorasani R, Fiskio J, Kuperman GJ, Bates DW. Automated Evidence-based Critiquing of Orders for Abdominal Radiographs: Impact on Utilization and Appropriateness. J Am Med Inform Assoc 1997; 04 (06) 511-21.
- 61 Chin HL, Wallace P. Embedding guidelines into direct physician order entry: simple methods, powerful results. Proc AMIA Symp 1999; 221-5.
- 62 Bates DW, Cullen DJ, Laird N, Petersen LA, Small SD, Servi D. et al. Incidence of adverse drug events and potential adverse drug events. Implications for prevention. ADE Prevention Study Group. Jama 1995; 274 (01) 29-34.
- 63 Chertow GM, Lee J, Kuperman GJ, Burdick E, Horsky J, Seger DL. et al. Guided medication dosing for inpatients with renal insufficiency. Jama 2001; 286 (22) 2839-44.
- 64 Bobb A, Gleason K, Husch M, Feinglass J, Yarnold PR, Noskin GA. The epidemiology of prescribing errors: the potential impact of computerized prescriber order entry. Arch Intern Med 2004; 164 (07) 785-92.
- 65 Evans RS, Pestotnik SL, Classen DC, Clemmer TP, Weaver LK, Orme Jr JF. et al. A Computer Assisted Management Program for Antibiotics and Other Antiinfective Agents. N Engl J Med 1998; 338 (04) 232-8.
- 66 Classen DC, Pestotnik SL, Evans RS, Lloyd JF, Burke JP. Adverse drug events in hospitalized patients. Excess length of stay, extra costs, and attributable mortality. Jama 1997; 277 (04) 301-6.
- 67 Tierney WM, Miller ME, Overhage JM, McDonald CJ. Physician inpatient order writing on microcomputer workstations. Effects on resource utilization. Jama 1993; 269 (03) 379-83.
- 68 Peterson JF, Kuperman GJ, Shek C, Patel M, Avorn J, Bates DW. Guided prescription of psychotropic medications for geriatric inpatients. Arch Intern Med 2005; 165 (07) 802-7.
- 69 Potts AL, Barr FE, Gregory DF, Wright L, Patel NR. Computerized physician order entry and medication errors in a pediatric critical care unit. Pediatrics 2004; 113 (1 Pt 1): 59-63.
- 70 Schiff GD, Klass D, Peterson J, Shah G, Bates DW. Linking laboratory and pharmacy: opportunities for reducing errors and improving care. Arch Intern Med 2003; 163 (08) 893-900.
- 71 Payne TH, Hoey PJ, Nichol P, Lovis C. Preparation and use of preconstructed orders, order sets, and order menus in a computerized provider order entry system. J Am Med Inform Assoc 2003; 10 (04) 322-9.
- 72 Bobb AM, Payne TH, Gross PA. Viewpoint: controversies surrounding use of order sets for clinical decision support in computerized provider order entry. J Am Med Inform Assoc 2007; 14 (01) 41-7.
- 73 Gross PA, Bates DW. A pragmatic approach to implementing best practices for clinical decision support systems in computerized provider order entry systems. J Am Med Inform Assoc 2007; 14 (01) 25-8.
- 74 Butler J, Speroff T, Arbogast PG, Newton M, Waitman LR, Stiles R. et al. Improved compliance with quality measures at hospital discharge with a computerized physician order entry system. Am Heart J 2006; 151 (03) 643-53.
- 75 Ash JS, Stavri PZ, Kuperman GJ. A consensus statement on considerations for a successful CPOE implementation. J Am Med Inform Assoc 2003; 10 (03) 229-34.
- 76 Bates DW, Kuperman GJ, Wang S, Gandhi T, Kittler A, Volk L. et al. Ten commandments for effective clinical decision support: making the practice of evidence-based medicine a reality. J Am Med Inform Assoc 2003; 10 (06) 523-30.
- 77 Teich JM, Osheroff JA, Pifer EA, Sittig DF, Jenders RA. The CDS Expert Review Panel. Clinical decision support in electronic prescribing: recommendations and an action plan: report of the joint clinical decision support workgroup. J Am Med Inform Assoc 2005; 12 (04) 365-76.
- 78 Miller RA, Gardner RM, Johnson KB, Hripcsak G. Clinical decision support and electronic prescribing systems: a time for responsible thought and action. J Am Med Inform Assoc 2005; 12 (04) 403-9.
- 79 McDonald CJ, Overhage JM, Mamlin BW, Dexter PD, Tierney WM. Physicians, information technology, and health care systems: a journey, not a destination. J Am Med Inform Assoc 2004; 11 (02) 121-4.
- 80 Aarts J, Doorewaard H, Berg M. Understanding implementation: the case of a computerized physician order entry system in a large Dutch university medical center. J Am Med Inform Assoc 2004; 11 (03) 207-16.
- 81 Coiera E. Four rules for the reinvention of health care. Bmj 2004; 328 (7449): 1197-9.
- 82 Georgiou A, Westbrook JI. Computerised order entry systems and pathology services a synthesis of the evidence. Clin Biochem Rev 2006; 27 (02) 79-87.
- 83 Beuscart-Zephir MC, Pelayo S, Anceaux F, Meaux JJ, Degroisse M, Degoulet P. Impact of CPOE on doctor-nurse cooperation for the medication ordering and administration process. Int J Med Inform 2005; 74 (7-8): 629-41.
- 84 Coiera E. When conversation is better than computation. J Am Med Inform Assoc 2000; 07 (03) 277-86.
- 85 Stead WW, Baker W, Harris TR, Hodges TM, Sittig DF. A fast track to IAIMS: the Vanderbilt University strategy. Proc Annu Symp Comput Appl Med Care 1992; 527-31.
- 86 Koppel R, Metlay JP, Cohen A, Abaluck B, Localio AR, Kimmel SE. et al. Role of computerized physician order entry systems in facilitating medication errors. Jama 2005; 293 (10) 1197-203.
- 87 Miller RA, Gardner RM. Recommendations for responsible monitoring and regulation of clinical software systems. American Medical Informatics Association, Computer-based Patient Record Institute, Medical Library Association, Association of Academic Health Science Libraries,American Health Information Management Association, American Nurses Association. J Am Med Inform Assoc 1997; 04 (06) 442-57.
- 88 Kuperman GJ, Bobb A, Payne TH, Avery AJ, Gandhi TK, Burns G. et al. Medication-related clinical decision support in computerized provider order entry systems: a review. J Am Med Inform Assoc 2007; 14 (01) 29-40.
- 89 Classen DC, Avery AJ, Bates DW. Evaluation and certification of computerized provider order entry systems. J Am Med Inform Assoc 2007; 14 (01) 48-55.
- 90 Nebeker JR, Hoffman JM, Weir CR, Bennett CL, Hurdle JF. High rates of adverse drug events in a highly computerized hospital. Arch Intern Med 2005; 165 (10) 1111-6.