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J Pediatr Infect Dis 2020; 15(02): 110-112
DOI: 10.1055/s-0038-1641604
Case Report
Georg Thieme Verlag KG Stuttgart · New York

A Rare Pathogen in Acute Appendicitis: Two Cases with Comamonas testosteroni Infection and Literature Review

Ayşe Sağmak Tartar
1   Department of Infectious Diseases and Clinical Microbiology, Firat University School of Medicine, Elazığ, Turkey
,
Tugay Tartar
2   Department of Pediatric Surgery, Firat University School of Medicine, Elazığ, Turkey
› Author Affiliations
Further Information

Publication History

09 November 2017

04 March 2018

Publication Date:
11 April 2018 (online)

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Abstract

Comamonas testosteroni (formerly Pseudomonas testosteroni) is a common environmental bacterium, which is not a part of the human microbiome. It is rarely found as an infectious agent in clinical practice. The bacterium has low virulence potency and rarely causes human disease. Although this agent is generally considered to be of low virulence, reports of infections with C. testosteroni are increasing. With the exception of intra-abdominal infections, C. testosteroni is mainly reported as an opportunistic pathogen in immunocompromised patients. However, C. testosteroni has also been reported as a pathogen in patients with appendicitis (especially when perforated), suggesting that this bacterium may belong to the normal intestinal microbiota of some individuals. In this article, we present two children with appendicitis in whom C. testosteroni was isolated from appendix tissue samples.

Keywords

Comamonas testosteroni - pediatric - infectious - acute appendicitis
 

  • References

  • 1 Farooq S, Farooq R, Nahvi N. Comamonas testosteroni: is it still a rare human pathogen?. Case Rep Gastroenterol 2017; 11 (01) 42-47
    CrossrefPubMedSearch in Google Scholar
  • 2 Tsui TL, Tsao SM, Liu KS. , et al. Comamonas testosteroni infection in Taiwan: reported two cases and literature review. J Microbiol Immunol Infect 2011; 44: 67-71
    CrossrefPubMedSearch in Google Scholar
  • 3 Farshad S, Norouzi F, Aminshahidi M, Heidari B, Alborzi A. Two cases of bacteremia due to an unusual pathogen, Comamonas testosteroni in Iran and a review literature. J Infect Dev Ctries 2012; 6: 521-525
    CrossrefPubMedSearch in Google Scholar
  • 4 Orsini J, Tam E, Hauser N, Rajayer S. Polymicrobial bacteremia involving Comamonas testosteroni . Case Rep Med 2014; 578127
    CrossrefPubMedSearch in Google Scholar
  • 5 Clinical and Laboratory Standards Institute. Performance Standards for Antimicrobial Susceptibility Testing; 25th Informational Supplement, CLSI Document M100–S25. Wayne, PA: Clinical and Laboratory Standards Institute; 2015
    Search in Google Scholar
  • 6 Willems A, De Vos P. Comamonas . In: Dworkin M, Falkow S, Schleifer KH, Stackebrandt E. , eds. The Prokaryotes. New York, NY: Springer; 2006: 723-736
    CrossrefSearch in Google Scholar
  • 7 Brady TB, Marcon MJ. Less commonly encountered nonenteric gram-negative bacilli. In: Long SS, Pickering LK, Prober CG. , eds. Principles and Practise of Pediatric Infectious Diseases. London: Churchill Livingstone; 2008: 828-831
    Search in Google Scholar
  • 8 Atkinson BE, Smith DL, Lockwood WR. Pseudomonas testosteroni septicemia. Ann Intern Med 1975; 83: 369-370
    PubMedSearch in Google Scholar
  • 9 Yasayancan N, Koseoglu HI. The 20th Comamonas testosteroni bacteremia case in the literature from Turkey: mortal and polymicrobial. A case report and literature review. EJMO 2017; 1 (03) 168-171
    PubMedSearch in Google Scholar
  • 10 Pekintürk N, Akgüneş A. A rare pathogen Comamonas testosteroni: case report and review of literature. J Health Sci Kou 2016; 2: 7-10
    PubMedSearch in Google Scholar
  • 11 Barbaro DJ, Mackowiak PA, Barth SS, Southern PM. Pseudomonas testosteroni infections: eighteen recent cases and a review of literature. Rev Infect Dis 1987; 9 (01) 124-129
    CrossrefPubMedSearch in Google Scholar
  • 12 Kong C, Chen J, Zou X, Zhang Y, Zhu L. Study on drug sensitivity against Comamonas testosteroni by Kirby-Bauer disk diffusion method [article in Chinese]. Zhong Nan Da Xue Xue Bao Yi Xue Ban 2016; 41 (08) 856-859
    PubMedSearch in Google Scholar
  • 13 Altun E, Kaya B, Taktakoğlu O. , et al. Comamonas testosteroni peritonitis secondary to dislocated intrauterine device and laparoscopic intervention in a continuous ambulatory peritoneal dialysis patient. Perit Dial Int 2013; 33 (05) 576-578
    CrossrefPubMedSearch in Google Scholar
  • 14 Parolin M, Baraldi M, Valentini E, Murer L, Vidal E. Comamonas testosteroni -associated peritonitis in a pediatric peritoneal dialysis patient. World J Nephrol 2016; 5 (02) 220-223
    PubMedSearch in Google Scholar
  • 15 Hung YM, Chang YT, Kao CH. Polymicrobial bacteremia involving Comamonas testosteroni in a patient on dialysis with acute appendicitis. Ther Apher Dial 2017; 21 (06) 637-638
    CrossrefPubMedSearch in Google Scholar
  • 16 Gul M, Ciragil P, Bulbuloglu E, Aral M, Alkis S, Ezberci F. Comamonas testosteroni bacteremia in a patient with perforated acute appendicitis. Short communication. Acta Microbiol Immunol Hung 2007; 54: 317-321
    CrossrefPubMedSearch in Google Scholar
  • 17 Bayhan Gİ, Tanır G, Karaman İ, Özkan Ş. Comamonas testosteroni: an unusual bacteria associated with acute appendicitis. Balkan Med J 2013; 30 (04) 447-448
    CrossrefPubMedSearch in Google Scholar
  • 18 Khalki H, Deham H, Taghouti A, Yahyaoui G, Mahmoud M. Comamonas testosteroni appendicitis. Med Mal Infect 2016; 46: 168-170
    CrossrefPubMedSearch in Google Scholar