Factors IXa, Xa, Xla and Activated Protein C Do Not Have Protein C Activating Ability in the Presence of Thrombomodulin

Thromb Haemost 1988; 59(02): 339
DOI: 10.1055/s-0038-1642787

Letters to the Editor

Schattauer GmbH Stuttgart

Factors IX_a, X_a, Xl_a and Activated Protein C Do Not Have Protein C Activating Ability in the Presence of Thrombomodulin

E Anne Thompson

Monash University, Department of Medicine Alfred Hospital, Prahran 3181, Australia

,

Hatem H Salem

Monash University, Department of Medicine Alfred Hospital, Prahran 3181, Australia

References
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2 Galvin JB, Kurosawa S, Moore K, Esmon CT, Esmon NL. Reconstitution of rabbit thrombomodulin into phospholipid vesicles . J Biol Chem 1987; 262: 2199-205
3 Thompson EtA, Salem HH. Inhibition by human thrombomodulin offactor X_a-mediated cleavage of prothrombin . J Clin Invest 1986; 78: 13-13
4 Kisiel W. Human plasma protein C: Isolationcharacterisation andmechanism of activation by alpha thrombin . J Clin Invest 1979; 64: 761-769
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8 Esmon NL, Esmon CT. Membrane dependence of factor X_a-thrombomodulin interaction. Blood. 1986 68. Suppl 01 (abstract 1259)