Severe Deep Vein Thrombosis in a 2-Year-Old Child with Protein S Deficiency

Thromb Haemost 1987; 58(04): 1089
DOI: 10.1055/s-0038-1646069

Letter to the Editor

Schattauer GmbH Stuttgart

V De Stefano

Istituto di Semeiotica Medica, Università Cattolica, Largo, Gemelli 8, I-00168 Roma, Italy

,

G Leone

Istituto di Semeiotica Medica, Università Cattolica, Largo, Gemelli 8, I-00168 Roma, Italy

,

R Ferrelli

Istituto di Semeiotica Medica, Università Cattolica, Largo, Gemelli 8, I-00168 Roma, Italy

,

G Marietti

^*Istituto di Clinica Pediatrica, Università Cattolica, Largo, Gemelli 8, I-00168 Roma, Italy

,

G Tortorolo

^*Istituto di Clinica Pediatrica, Università Cattolica, Largo, Gemelli 8, I-00168 Roma, Italy

,

B Bizzi

Istituto di Semeiotica Medica, Università Cattolica, Largo, Gemelli 8, I-00168 Roma, Italy

,

R M Bertina

^**Haemostasis and Thrombosis Research Unit, Department of Haematology, University Hospital, Rijnsburgerweg 10, NL-2333 AA Leiden, The Netherlands

References
1 Schwarz HP, Fischer M, Hopmeier P, Batard MA, Griffin JH. Plasma protein S deficiency in familial thrombotic disease. Blood 1984; 64: 1297-1300
2 Comp PC, Esmon CT. Recurrent venous thromboembolism in patients with a partial deficiency of protein S. N Engl J Med 1984; 311: 1525-1528
3 Comp PC, Nixon RR, Cooper MR, Esmon CT. Familial protein S deficiency is associated with recurrent thrombosis. J Clin Invest 1984; 74: 2082-2088
4 Broekmans AW, Bertina RM, Reinalda-Poot J, Engesser L, Muller HP, Leeuw JA, Michiels JJ, Brommer E JP, Briet E. Hereditary protein S deficiency and venous thromboembolism. A study in three Dutch families. Thromb Haemostas 1985; 53: 273-7
5 Sas G, Blasko G, Petro I, Griffin JH. A protein S deficient family with portal vein thrombosis. Thromb Haemostas 1985; 54: 724
6 Bertina RM. Hereditary protein S deficiency. Haemostasis 1985; 15: 241-6
7 Mannucci PM, Tripodi A, Bertina RM. Protein S deficiency associated with “juvenile” arterial and venous thromboses. Thromb Haemostas 1986; 55: 440
8 Gladson CL, Griffin JH, Hach V, Beck KH, Scharrer I. The incidence of protein C and protein S deficiency in 139 young thrombotic patients. Blood 1985; 66 (suppl.) (01) 350a