Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00035024.xml
Thromb Haemost 1993; 70(01): 168-171
DOI: 10.1055/s-0038-1646182
DOI: 10.1055/s-0038-1646182
State-of-the-Art Lecture
Thrombin
Protease Nexin-1 and Thrombin: Injury-related Processes in the Brain
Further Information
Publication History
Publication Date:
03 July 2018 (online)
-
References
- 1 Glenn K, Carney D, Fenton J, Cunningham D. Thrombin active-site regions required for fibroblast receptor binding and initiation of cell division. J Biol Chem 1980; 255: 6609-16
- 2 Bar-Shavit R, Kahn A, Mudd M, Wilner G, Mann K, Fenton J. Monocyte chemotaxis: stimulation by specific exosite region in thrombin. Science 1983; 220: 728-31
- 3 Gurwitz D, Cunningham D. Thrombin modulates and reverses neuroblastoma neurite outgrowth. Proc Natl Acad Sci USA 1988; 85: 3440-44
- 4 Grand R, Grabham P, Gallimore M, Gallimore P. Modulation of morphological differentiation of human neuroepithelial cells by serine proteases: Independence from blood coagulation. EMBO J 1989; 8: 2209-15
- 5 Cavanaugh K, Gurwitz D, Cunningham D, Bradshaw R. Reciprocal modulation of astrocyte stellation by thrombin and protease nexin-1. J Neurochem 1990; 54: 1735-43
- 6 Nelson R, Siman R. Thrombin and its inhibitors regulate morphological and biochemical differentiation of astrocytes in vitro. Dev Brain Res 1990; 54: 93-104
- 7 Vu TK, Hung D, Wheaton V, Coughlin S. Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell 1991; 64: 1057-68
- 8 Suidan H, Stone S, Hemmings B, Monard D. Thrombin causes neurite retraction in neuronal cells through activation of cell surface receptors. Neuron 1992; 8: 363-75
- 9 Grabham P, Cunningham D. Thrombin receptor activating peptides regulate astrocyte stellation and proliferation (submitted).
- 10 Scott R, Bergman B, Bajpai A, Hersh R, Rodriguez H, Jones B, Watts S, Baker J. Protease nexin: Properties and a modified purification procedure. J Biol Chem 1985; 260: 7029-34
- 11 Low D, Baker J, Koonce W, Cunningham D. Released protease nexin regulates cellular binding, internalization and degradation of serine proteases. Proc Natl Acad Sci USA 1981; 78: 2340-44
- 12 Wagner S, Lau A, Cunningham D. Binding of protease nexin-1 to the fibroblast surface alters its specificity. J Biol Chem 1989; 264: 611-15
- 13 Low D, Scott R, Baker J. Cunningham: Cells regulate their mitogenic response to thrombin through release of protease nexin. Nature 1982; 298: 476-78
- 14 Gloor S, Odink K, Guenther J, Nick H, Monard D. A glia-derived neurite promoting factor with protease inhibitory activity belongs to protease nexins. Cell 1986; 47: 687-93
- 15 McGrogan M, Gohari J, Li M, Hsu C, Scott R, Simonsen C, Baker J. Molecular cloning and expression of two forms human protease nexin-1. Biotechnology 1988; 6: 172-77
- 16 Choi B, Suzuki M, Taiseung K, Wagner S, Cunningham D. Protease nexin-1: Localization in the human brain sugests a protective role against extravasated serine proteases. Am J Path 1990; 137: 741-47
- 17 Dihanich M, Kaser M, Reinhard E, Cunningham D, Monard D. Prothrombin mRNA is expressed by cells of the nervous system. Neuron 1991; 6: 575-81
- 18 Hoffman MC, Nitsch C, Scotti A, Reinhard E, Monard D. The prolonged presence of glia-derived nexin, an endogenous protease inhibitor, in the hippocampus after ischemia-induced delayed neuronal death. Neuroscience 1992; 49: 397-408
- 19 Vaughan P, Cunningham D. Regulation of protease nexin-1 synthesis and secretion in cultured brain cells by injury-related factors. J. Biol. Chem. 1993 in press