Antibody to Hepatitis C Virus after a Vapor Heated Factor VIII Concentrate - Lack of Evidence – Rebuttal

Thromb Haemost 1991; 66(05): 621-622
DOI: 10.1055/s-0038-1646472

Letter to the Editor

Schattauer GmbH Stuttgart

P M Mannucci

A. Bianchi Bonomi, Hemophilia and Thrombosis Center and Institute of Internal Medicine, IRCCS Maggiore Hospital and University Milano, Italy

,

M Colombo

A. Bianchi Bonomi, Hemophilia and Thrombosis Center and Institute of Internal Medicine, IRCCS Maggiore Hospital and University Milano, Italy

,

A R Zanetti

¹Institute of Virology, University of Milan, Italy

References
1 Mannucci PM, Zanetti AR, Colombo M, Chistolini A, De Biasi R, Musso R, Tamponi G. Antibody to hepatitis C virus after a vapour-heated factor VIII concentrate. Thromb Haemostas 1990; 64: 232-4
2 Mannucci PM, Zanetti AR, Colombo M. and the Study Group of the Fondazione dell'Emofilia Prospective study of hepatitis after factor VIII concentrates exposed to hot vapour. Br J Haematol 1988; 68: 427-30
3 Colombo M, Rumi MG, Mannucci PM. Specificity of hepatitis C antibody ELISA in patients with haemophilia. Lancet 1990; 335: 1345 (letter)
4 Colombo M, Mannucci PM, Carnelli V, Savidge GT, Gazangel C, Schimpf K. Transmission of non-A, non-B hepatitis by heat-treated factor VIII concentrate. Lancet 1985; 2: 1-3
5 Hollinger FB, Dolana G, Thomas W, Gyorkey F. Reduction in risk of hepatitis transmission by heat-treatment of a human factor VIII concentrate. J Infect Dis 1984; 150: 250-62
6 Eibl J, Eder G, Anderle K. Issues associated with safety testing of blood products in endemic areas. Br J Haematol 1989; 69: 575-576 (letter)