Direct Proof of Extreme Lyonization as a Cause of Low Factor VIII Levels in Females

• References

• 1 Barrow EM, Graham JB. 1974; Blood coagulation factor VIII (antihemophilic factor): with comments on von Willebrand’s disease and Christmas disease. Physiological Reviews 54: 23
• 2 Holmberg L, Nilsson IM. 1977 Healthy son to a woman with severe hemophilia B. First Florence Conference in Haemostasis and Thrombosis, Abstract Book 111
• 3 Lyon MT. 1962; Sex duration and gene action in the mammalian X-chromosome. American Journal of Human Genetics 14: 135
• 4 Revesz T, Schuler D, Goldschmidt B, Elodi S. 1972; Christmas disease in on of a pair of monozygotic twins possibly the effect of lyonization Journal of Medical Genetics. 9: 396