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Thromb Haemost 1979; 41(03): 529-536
DOI: 10.1055/s-0038-1646805
Original Articles
Schattauer GmbH Stuttgart

Studies on a Subcellular System for Vitamin K- Dependent Carboxylation

R Wallin
The Institute of Medical Biology, University of Tromso, Tromso, Norway
,
H Prydz
The Institute of Medical Biology, University of Tromso, Tromso, Norway
› Author Affiliations
Further Information

Publication History

Received 24 November 1977

Accepted 12 May 1978

Publication Date:
24 July 2018 (online)

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Summary

The subcellular localization of acarboxyprothrombin and the vitamin K-dependent carboxylation system has been studied using livers from vitamin K-deficient rats and found to be mainly in the membranes of the rough microsomal fraction. Bovine acarboxyprothrombin or fragment 1 thereof were inactive as substrates in the rat carboxylating sytem.

 

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