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Thromb Haemost 1990; 64(04): 604
DOI: 10.1055/s-0038-1647366
Letter to the Editor
Schattauer GmbH Stuttgart

Normal Platelet Function, but Increased Platelet Activation In Vivo in Diabetic Patients

Letizia Tomaselli
Istituto di Ricerche Farmacologiche Mario Negri Consorzio Mario Negri Sud 66030 Santa Maria Imbaro, Italy
,
Chiara Cerletti
Istituto di Ricerche Farmacologiche Mario Negri Consorzio Mario Negri Sud 66030 Santa Maria Imbaro, Italy
,
Giovanni de Gaetano
Istituto di Ricerche Farmacologiche Mario Negri Consorzio Mario Negri Sud 66030 Santa Maria Imbaro, Italy
,
Alberto Notarbartolo
1   Patologia Medica, Università di Palermo, Italy
,
Giovanni Davì
2   Cattedra di Ematologia, Università di Chieti, Italy
,
Mario Pupillo
3   Ospedale Civile “F. Renzetti”, Lanciano Italy
› Author Affiliations
Further Information

Publication History

Received 20 June 1990

Accepted 16 July 1990

Publication Date:
25 July 2018 (online)

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  • References

  • 1 Mustard JF, Packham MA. Platelets and diabetes mellitus. N Engl J Med 1984; 311: 665-667
    CrossrefPubMedGoogle Scholar
  • 2 Rao KA, Goldberg RF, Walsh PN. Platelet coagulant activities in diabetes mellitus: evidence for relationship between platelet coagulant hyperactivity and platelet volume. J Lab Clin Med 1984; 103: 82-92
    PubMedGoogle Scholar
  • 3 Kazmier FJ, Bowie EJ W, O’Fallow WM, Zimmermann BR, Osmundson PJ, Palumbo PJ. A prospective study of peripheral occlusive arterial disease in diabetes. IV. Platelet and plasma functions. Mayo Clin Proc 1981 56. 243-253
    PubMedGoogle Scholar
  • 4 Allessandrini P, McRae J, Feman S, FitzGerald GA. Thromboxane biosynthesis and platelet function in type I diabetes mellitus. N Engl J Med 1988; 319: 208-212
    CrossrefPubMedGoogle Scholar
  • 5 Davi G, Catalano I, Perez T, Notarbartolo A, Strano A, Ciabattoni G, Patrono C. Increased urinary excretion of 11-dehydro-thromboxane B2 in type 2 diabetes mellitus. Thromb Haemostas 1989; 62: 244
    PubMedGoogle Scholar
  • 6 FitzGerald GA, Smith B, Pedersen AK, Brash AR. Increased prostacyclin biosynthesis in patients with severe atherosclerosis and platelet activation. N Engl J Med 1984; 310: 1065-1068
    CrossrefPubMedGoogle Scholar
  • 7 Cerletti C, Minoldo S, Bucchi F, Del Maschio A, de Gaetano G. Requirement of ADP for arachidonic acid-induced platelet aggregation: studies with selective thromboxane-synthase inhibitors. Biochem Pharmacol 1986; 35: 1201-1203
    CrossrefPubMedGoogle Scholar
  • 8 Ciabattoni G, Maclouf J, Catella F, FitzGerald GA, Patrono C. Radioimmunoassay of 11-dehydrothromboxane B2 in human plasma and urine. Biochim Biophys Acta 1987; 918: 293-297
    CrossrefPubMedGoogle Scholar
  • 9 Di Minno G, Silver MJ, Cerbone AM, Murphy S. Trial of repeated low-dose aspirin in diabetic angiopathy. Blood 1986; 68: 886-891
    PubMedGoogle Scholar