Rapid Detection and Quantitation of Precipitating Streptokinase-Antibodies

F Spöttl; R Kaiser

doi:10.1055/s-0038-1647730

Subscribe to RSS

Please copy the URL and add it into your RSS Feed Reader.

https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00035024.xml

Share / Bookmark

Facebook Linkedin Weibo

Download PDF

Thromb Haemost 1974; 32(02/03): 608-616
DOI: 10.1055/s-0038-1647730

Original Article

Schattauer GmbH

Rapid Detection and Quantitation of Precipitating Streptokinase-Antibodies

F Spöttl

¹Department of Internal Medicine (Head: Doz. Dr. F. Spöttl), Allgemeines, Öffentliches Krankenhaus Schärding, Austria

,

R Kaiser

¹Department of Internal Medicine (Head: Doz. Dr. F. Spöttl), Allgemeines, Öffentliches Krankenhaus Schärding, Austria

› Author Affiliations

Further Information

Publication History

Received 17 June 1974

Accepted 25 July 1974

Publication Date:
24 July 2018 (online)

Also available at

Abstract
Full Text
References

Buy Article Permissions and Reprints

Summary

Streptokinase-therapy is regularly followed by a marked increase of precipitating streptokinase-antibodies. These antibodies cause a significant inhibition of streptokinase-induced plasminogen activation. Counterelectrophoresis is a useful method of tracing the antibodies in serum. For quantitative estimation a modified radial immunodiffusion method is presented. The antibodies were identified as IgG.

References
1 Amery A, Maes H, Yeemylen J, Verstraete M. 1963; The streptokinase reactivity test (SKRT). Thrombosis et Diathesis Haemorrhagica 09: 175.

PubMed Search in Google Scholar
2 Bett J. H. N, Biggs J. C, Castaldi P. A, Chesterman C. N, Hale G. S, McLean K. H, Morgan J. J, O’Sullivan E. F, Rosenbaum M. 1973; Australian multicentre trial of streptokinase in acute myocardial infarction. Lancet 01: 57.

PubMed Search in Google Scholar
3 Breddin K, Ehrly A. M, Fechler L, Frick D, König H, Kraft H, Krause H, Krzywanek H. J, Kutschera J, Lösch H. W, Ludwig O, Mikat B, Rausch F, Rosenthal P, Sartory S, Voigt G, Wylicil P. 1973; Die Kurzzeitfibrinolyse beim akuten Myocardinfarkt. Deutsche medizinische Wochenschrift 98: 861.

Thieme Connect PubMed Search in Google Scholar
4 Burnet F. M, Fenner F. 1949. The Production of Antibodies. Macmillan; Melbourne: 2nd. Ed..

Search in Google Scholar
5 Bussard A. 1959; Description d’une technique combinant simultanément l’électro-phorèse et la précipitation immunologique dans un gel: l’électrosynèrése. Biochemica et Biophysica Acta 34: 258.

PubMed Search in Google Scholar
6 Deutsch E, Fischer M. 1960; Die Wirkung intravenös applizierter Streptokinase auf Fibrinolyse und Blutgerinnung. Thrombosis et Diathesis Haemorrhagica 04: 482.

PubMed Search in Google Scholar
7 European Working Party. 1971; Streptokinase in recent myocardial infarction: A controlled multicentre trial. British Medical Journal 02: 325.

PubMed Search in Google Scholar
8 Fletcher A. P, Alkjaersig N, Sherry S. 1958; The clearance of heterologous protein from the circulation in normal and immunized man. Journal of Clinical Investigation 37: 1306.

Crossref PubMed Search in Google Scholar
9 Fletcher A. P, Alkjaersig N, Sherry S. 1959; The maintenance of a sustained thrombolytic state in man. I. Induction and effects. Journal of Clinical Investigations 38: 1096.

PubMed Search in Google Scholar
10 Gross R. 1962; Einige klinische Aspekte von Fibrinolyse und Thrombolyse. Behring -werk-Mitteilungen 41: 68.

PubMed Search in Google Scholar
11 Gross R, Hartl W, Kloss G, Rahn B. 1960; Thrombolyse durch Infusion hochgereinigter Streptokinase. Deutsche medizinische Wochenschrift 85: 2129.

Thieme Connect PubMed Search in Google Scholar
12 Heimburger N, Schwick G. 1962; Die Fibrinagar-Elektrophorese. Thrombosis et Diathesis Haemorrhagica. 07: 432.

PubMed Search in Google Scholar
13 Hiemeyer V, Rasche H, Diehl K. 1969; Der Einfluß von Antikoagulantien und Streptokinase auf den Verlauf des akuten Herzinfarktes. Klinische Wochenschrift 47: 371.

Crossref PubMed Search in Google Scholar
14 Hirsh J, O’Sullivan E. F, Martin M. 1970; Evaluation of a standard dosage schedule with streptokinase. Blood 35: 341.

PubMed Search in Google Scholar
15 Ludwig H. 1971; Thrombolytic therapy in pregnancy. Experimental and clinical studies. Thrombosis et Diathesis Haemorrhagica Suppl. 47, 243.

PubMed Search in Google Scholar
16 Mancini G, Carbonara A. O, Heremans J. F. 1965; Immunological quantitation of antigens by single radial immunodiffusion. Immunochemistry 02: 235.

Crossref PubMed Search in Google Scholar
17 Nilsson I. M, Olow B. 1962; Fibrinolysis induced by streptokinase in man. Acta Chirurgica Scandinavica 123: 247.

PubMed Search in Google Scholar
18 Paraskevas M, Nilsson I. M, Martinsson G. 1962; A method for determining serum inhibitors of plasminogen activation. Scandinavian Journal of Clinical and Laboratory Investigation 14: 138.

Crossref PubMed Search in Google Scholar
19 Pesendorfer F, Krassnitzky O, Wewalka F. 1970; Immunelektrophoretischer Nachweis von “Hepatitis associated antigen” (Au/SH-Antigen). Klinische Wochenschrift 48: 58.

Crossref PubMed Search in Google Scholar
20 Scheidegger J. J. 1955; Une micro-méthode de l’immuno-electrophorése. International Archives of Allergy 07: 103.

Crossref PubMed Search in Google Scholar
21 Schmutzler R, Fritze E, Gebauer D, Gillmann H, Heckner F, Körtge P, van de Loo J, Pezold F. A, Poliwoda H, Praetorius F, Zekorn D. 1971; Fibrinolytic therapy in acute myocardial infarction. Thrombosis et Diathesis Haemor-rhagica, Suppl 47: 211.

PubMed Search in Google Scholar
22 Spöttl F, Holzknecht F. 1970; The influence of inhibitors of plasmin and plasminogen activation on the streptokinase-induced fibrinolytic state. Thrombosis et Diathesis Haemorrhagica 24: 100.

PubMed Search in Google Scholar
23 Spöttl F, Holzknecht F. 1972. Die Hemmung der Streptokinase-induzierten Plasminogenaktivierung. 3. Kongress der Österreichischen liämatologischen Gesellschaft. Klagenfurt; 1972..

Search in Google Scholar
24 Spöttl F, Kaiser R, Mosuni M. S. 1974; Acute phase reaction following intravenous administration of streptokinase. Thrombosis et Diathesis Haemorrhagica 31: 429.

PubMed Search in Google Scholar
25 Stacher A, Böhnel J. 1961; Die Dosierung der Streptokinase bei fibrinolytischer Therapie. Wiener klinische Wochenschrift 39: 665.

PubMed Search in Google Scholar
26 Thies H. A. 1964; II. Streptokinase-Kolloquium, Bad Nauheim 1964, Diskussion. Behringwerk-Mitteilungen 44: 59.

PubMed Search in Google Scholar
27 Tillet S, Garner R. L. 1933; The fibrinolytic activity of hemolytic streptococci. Journal of Experimental Medicine 68: 488.

PubMed Search in Google Scholar
28 Tillet W. S, Edwards L. B, Garner R. L. 1934; Fibrinolytic activity of hemolytic streptococci. The development of resistance to fibrinolysis following acute hemolytic streptococcus infection. Journal of Clinical Investigations 13: 47.

PubMed Search in Google Scholar
29 Verstraete M, Vermylen J, Amery A, Vermylen C. 1966; Thrombolytic therapy with streptokinase using a standard dosage scheme. British Medical Journal 01: 454.

Crossref PubMed Search in Google Scholar
30 Witte S. 1963; Klinische Erfahrungen über die Dosierung der fibrinol y tischen Therapie. Thrombosis et Diathesis Haemorrhagica, Suppl 03: 189.

PubMed Search in Google Scholar

Subscribe to RSS

Share / Bookmark

Rapid Detection and Quantitation of Precipitating Streptokinase-Antibodies

Publication History

Summary

References