Release of Fibrinopep tides from Fibrinolytic Fibrinogen Fragment E

A Peyer; P. W Straub

doi:10.1055/s-0038-1647773

Thrombosis and Haemostasis, Table of Contents

Thromb Haemost 1973; 29(02): 300-312
DOI: 10.1055/s-0038-1647773

Original Article

Schattauer GmbH

Release of Fibrinopep tides from Fibrinolytic Fibrinogen Fragment E

A Peyer

¹Department of Medicine, Kantonsspital, University of Zurich Zurich, Switzerland

,

P. W Straub

¹Department of Medicine, Kantonsspital, University of Zurich Zurich, Switzerland

› Author Affiliations

Abstract

Purified “terminal” proteolytic E fragments of fibrinogen and fibrin as produced by plasmin digestion were treated with thrombin. Thrombin treatment of fragment E obtained from fibrinogen, liberated both fibrinopeptides A and B and sometimes AP. Thrombin treatment of fragment E obtained from Reptilase-clotted fibrin liberated only fibrinopeptide B. From fragments E derived from thrombin-clotted fibrin as well as from fragments D obtained from either fibrinogen, thrombin-fibrin or Reptilase - fibrin no fibrinopeptides could be recovered.

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References

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