Age Related Changes in Protein C Activity in Healthy Adult Males

Thromb Haemost 1991; 65(03): 326-327
DOI: 10.1055/s-0038-1648145

Letter to the Editor

Schattauer GmbH Stuttgart

R C Tait

Department of Haematology, Royal Infirmary, Glasgow G4 0SF, Scotland

,

Isobel D Walker

Department of Haematology, Royal Infirmary, Glasgow G4 0SF, Scotland

,

S I A Islam

^*Glasgow and west of scotland Blood Transfusion Service, Law Hospital, Carluke, Scotland

,

R Mitchell

^*Glasgow and west of scotland Blood Transfusion Service, Law Hospital, Carluke, Scotland

,

J A Conkie

Department of Haematology, Royal Infirmary, Glasgow G4 0SF, Scotland

,

Frances McCall

Department of Haematology, Royal Infirmary, Glasgow G4 0SF, Scotland

,

J F Davidson

Department of Haematology, Royal Infirmary, Glasgow G4 0SF, Scotland

References
1 Griffin JH, Evatt B, Zimmerman TS, Kleiss AJ, Wideman C. Deficiency of protein C in congenital thrombotic disease. J Clin Invest 1981; 68: 1370-1373
2 Miletich J, Sherman L, Broze G. Absence of thrombosis in subjects with heterozygous protein C deficiency. N Engl J Med 1987; 317: 991-996
3 Broekmans AW, van der Linden IK, Veltkamp JJ, Bertina RM. Prevalence of isolated protein C deficiency in patients with venous thrombotic disease and in the population. Thromb Haemostas 1983; 50: 350 Abstr
4 Gladson CL, Scharrer I, Hach V, Beck KH, Griffin JH. The frequency of type I heterozygous protein S and protein C deficiency in 141 unrelated young patients with venous thrombosis. Thromb Haemostas 1988; 59: 1822
5 Broekmans AW. Hereditary protein C deficiency. Haemostasis 1985; 15: 233-240
6 Andrew M, Paes B, Milner R, Johnstotr M, Mitchell L, Tollefson DM, Powers P. Development of the human coagulation system in the fullterm infant. Blood 1987; 70: 165-172
7 Nardi M, Karpatkin M. Prothrombin and protein C in early childhood: normal adult levels are not achieved until the fourth year of life. J Pediatr 1986; 109: 843-845
8 McCall F, Conkie JA, Walker ID, Davidson JE. Measurement of protein C in plasma - a fully automated assay. Thromb Res 1987; 45: 681-685
9 Kemkes-Matthes B. Heterozygous protein C deficiency type I. Blut 1989; 58: 201-206