Mecanismo de Frank Starling: una visión aplicada en la erección del pene

Nathalia Buitrago Gómez; Johnie Smith Husbands; Herney Andrés García-Perdomo

doi:10.1055/s-0038-1648238

Revista Urología Colombiana / Colombian Urology Journal, Inhaltsverzeichnis

CC BY-NC-ND 4.0 · Revista Urología Colombiana / Colombian Urology Journal 2019; 28(02): 183-188
DOI: 10.1055/s-0038-1648238

Review Articles | Artículos de Revisión

Sociedad Colombiana de Urología. Publicado por Thieme Revinter Publicações Ltda Rio de Janeiro, Brazil

Mecanismo de Frank Starling: una visión aplicada en la erección del pene

Frank-Starling Mechanism: A Vision Applied To Penile Erection

Nathalia Buitrago Gómez

¹Médico, Universidad Libre, Cali, Valle del Cauca, Colombia

,

Johnie Smith Husbands

²Anestesiólogo, Universidad del Valle, Universidad Libre, Cali, Valle del Cauca, Colombia

,

Herney Andrés García-Perdomo

³Asociado Escuela de Medicina, Universidad del Valle, Director Grupo de Investigación UROGIV y Grupo Asociado Cochrane, Cali, Valle del Cauca, Colombia

› Institutsangaben

Abstract

Resumen

El mecanismo de Frank-Starling es un concepto básico de la fisiología cardíaca y su aprendizaje. Constituye la base fundamental para el entendimiento del funcionamiento del corazón y patologías prevalentes y con alta morbimortalidad como lo es la insuficiencia cardíaca. Por lo cual, su relación con un proceso más interactivo como la erección del pene, podría asegurar un aprendizaje perdurable y práctico. La relación se fundamentó en el reemplazo del eje X de la curva por precarga en el caso del corazón y estimulación en el caso del pene, para así lograr una relación incluso con la disfunción eréctil, que sería el equivalente a la insuficiencia cardíaca. De esa manera, se encontró que a mayor estimulación hay mayor erección y a mayor precarga hay mayor eyección ventricular, teniendo ambas curvas una meseta. Asímismo, farmacológicamente, se encontró relación con el uso de estimulación β-adrenérgica y de inhibidores selectivos de la fosfodiesterasa tipo 5 como el sildenafil, los cuales desplazan la curva hacia arriba y a la izquierda.

Abstract

The Frank-Starling mechanism is a basic concept of cardiac physiology and the fundamental basis for understanding the cardiac performance and prevalent disorders at risk of high morbidity and mortality, such as heart failure. Therefore, its relation with an interactive process like penile erection may enable deeper insight into cardiac physiology. The X-axis of Frank-Starling's curve was changed from ventricular end-diastolic volume to stimulation, to achieve a relation that includes erectile dysfunction, which is the equivalent of heart failure. A direct relationship was found between stimulation and erection, as well as end-diastolic volume and ventricular ejection with a plateau in both curves. Likewise, pharmacologically, a relation was identified with the use of β-adrenergic and selective inhibitor of phosphodiesterase (PDE) type 5 like sildenafil, which shift leftward and upward the Frank-Starling curve.

Palabras Clave

insuficiencia cardíaca - erección peniana - disfunción eréctil

Keywords

heart failure - penile erection - erectile dysfunction

Volltext

Referenzen

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