Subscribe to RSS
DOI: 10.1055/s-0038-1648675
Heparin-Neutralizing Activity, Total Progressive Antithrombin and the Ethanol Gel Test in Acute Chest Pain
Publication History
Received 07 December 1977
Accepted 16 January 1978
Publication Date:
12 July 2018 (online)
Summary
92 patients admitted to a cardiac monitoring unit with chest pain were investigated. The mean heparin-neutralizing activity of the 34 patients with severe myocardial infarction was found to be significantly different from the mean of 70 normal controls. However, there was considerable overlap between individual observations and the normal range. Only 5 of the 34 patients with severe myocardial infarction had antithrombin levels outside the normal range. In patients with a severe myocardial infarct tested on the 2nd and 3rd day after infarction there was a significant increase in the number of positive ethanol gel tests compared with the other patients studied.
-
References
- 1 Armesen H, Faeerhol MK. 1972; alpha 2 macroglobulin, alpha-I-antitrypsin and antithrombin III in plasma and serum during fibrinolytic therapy with urokinase. Scandinavian Journal of Clinical and Laboratory Investigation. 29: 259
- 2 Godal HC, Abildgaard U, Kierulf P. 1971; Ethanol gelation and fibrin monomers in plasma. Scandinavian Journal of Haematology Suppl 13: 189
- 3 Lane JL, Bird P, Rizza CR. 1975; A new assay for the measurement of total progressive antithrombin. British Journal of Haematology 30: 103
- 4 Nowak A, Lipinsiki B, Drzewiecki J. 1972; Levels of soluble fibrin monomer complexes in the course of myocardial infarction. British Haematology Journal 34: 593
- 5 O’Brien JR, Etherington N, Jamieson S, Klaber MR, Lincoln SV. 1974; Platelet function long after arterial and venous thrombosis. Thrombosis et Diathesis Haemorrhagica 31: 279
- 6 O’Brien JR, Etherington M, Jamieson S, Lawford P, Susses J, Lincoln SV. 1975; Heparin neutralising activity test in the diagnosis of acute myocardial infarction. Journal of Clinical Pathology 28: 975
- 7 Yue RH, Gertler MM, Starr T, Koutrouby R. 1976; Alteration of plasma antithrombin III levels in ischaemic heart disease. Thrombosis and Haemostasis 35: 598
- 8 Murray TS, Lorimer AR, Cox FC, Lawrie TD V. 1970; Leg vein thrombosis following myocardial infarction. Lancet II 792