Thromb Haemost 1994; 72(04): 649-650
DOI: 10.1055/s-0038-1648934
Letter to the Editor
Schattauer GmbH Stuttgart

Measurement of Activated Factor VII Using Soluble Mutant Tissue Factor -Proposal for Standardization

Anthony R Hubbard
Division of Haematology, National Institute for Biological Standards and Control, Potters Bar, Herts., UK
,
Trevor W Barrowcliffe
Division of Haematology, National Institute for Biological Standards and Control, Potters Bar, Herts., UK
› Author Affiliations
Further Information

Publication History

Received 16 May 1994

Accepted after revision 14 June 1994

Publication Date:
06 July 2018 (online)

 
  • References

  • 1 Morrissey JH, Macik BG, Neuenschwander PF, Comp PC. Quantitation of activated factor VII levels in plasma using a tissue factor mutant selectively deficient in promoting factor VII activation. Blood 1993; 81: 734-744
  • 2 Hubbard AR, Parr LJ. Potency estimation of activated factor VII concentrates. Thromb Haemost 1991; 65: 1160
  • 3 Kitchen S, Malia RG, Preston FE. A comparison of methods for the measurement of activated factor VII. Thromb Haemost 1992; 68: 301-395
  • 4 Hedner U, Ljundberg J, Lund-Hansen T. Comparison of the effect of plasma-derived and recombinant human FVIIa in vitro and in a rabbit model. Blood Coag Fibrinol 1990; 1: 145-152
  • 5 WHO Expert Committee on Biological Standardization. Forty-third report. WHO Technical Report Series, No 840 1994