Inhibition of Thrombin Generation by Aspirin

• References

• 1 Patrono C. Aspirin as an antiplatelet drug. New Engl J Med 1994; 330: 1287-94
• 2 Vane JR, Flower RJ, Botting RM. The mechanism of action of aspirin. In: Aspirin and other salicylates Vane JR, Botting RM. eds. London, UK: Chapman & Hall; 1992: 35-62
• 3 Szczeklike A, Krzanowski M, Gora P, Radwan J. Antiplatelet drugs and generation of thrombin in clotting blood. Blood 1992; 80: 2006-11
• 4 Ratnatunga CP, Edmondson SF, Rees GM, Kovacs IB. High-dose aspirin inhibits shear-induced platelet reaction involving thrombin generation. Circulation 1992; 85: 1077-82
• 5 Szczeklik A, Dropinski J, Gora P. Serum immunoglobulin E and sudden cardiac arrest during myocardial infarction. Coronary Artery Dis 1993; 4: 1029-32
• 6 Kessels H, Béguin S, Andree H, Hemker HC. Measurement of thrombin generation in whole blood - the effect of heparin and aspirin. Thromb Haemost 1994; 72: 78-84
• 7 Kyrle PA, Westwick J, Scully MF, Kakkar VV, Levis GP. Investigation of the interaction of blood platelets with the coagulation system at the site of plug formation ex-vivo in man Effect of low-dose aspirin. Thromb Haemost 1987; 57: 62-9
• 8 Szczeklik A, Musial J, Undas A, Swadzba J, Gora P, Duplaga M. Aspirin inhibits thrombinogenesis in normocholesterolemic but not in hypercholes-terolemic men. Thromb Haemost 1993; 69: 797-798