Summary
The plasminogen-streptokinase complex called “activator” was present in diluted plasma
in the form of a largely dissociated mixture. More than ⅞ of the streptokinase and
plasminogen molecules were available for further activator formation.
The activator is probably a dissociated complex of the formula
Streptokinase + Plasminogen ⇄ Activator.
The fact that an increase in activator concentration by x times is obtained by multiplying
either the streptokinase content by the factor y or the plasminogen concentration
by the same factor y would point to a kinetic effect along the lines of the mass action
law.
