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Thromb Haemost 1973; 30(03): 471-479
DOI: 10.1055/s-0038-1649125
Original Article
Schattauer GmbH

The Measurement of Heparin

A Method Based on the Potentiation of Anti-Factor Xa
K. W. E Denson
1   John Radcliffe Hospital, Oxford
,
John Bonnar
1   John Radcliffe Hospital, Oxford
› Author Affiliations
Further Information

Publication History

Received 24 July 1973

Accepted 20 August 1973

Publication Date:
30 June 2018 (online)

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Summary

A method for the measurement of heparin utilising the potentiating effect of heparin on the action of anti-factor Xa is described. The effect on the assay of platelet contamination of plasma, the presence of fibrinogen degradation products and low levels of anti-factor Xa have been studied. The assay method has been compared with the calcium thrombin time method and a group of obstetrical patients have been studied using both methods.

 

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