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Thromb Haemost 1977; 37(01): 086-090
DOI: 10.1055/s-0038-1649205
Original Article
Schattauer GmbH

A Comparison of Coagulation Factor Replacement with and without Prednisolone in the Treatment of Haematuria in Haemophilia and Christmas Disease

C. R Rizza
1   Oxford Haemophilia Centre Churchill Hospital, Oxford
2   Lord Mayor Treloar College, Alton, Hampshire, England
,
P. B. A Kernoff   *
1   Oxford Haemophilia Centre Churchill Hospital, Oxford
2   Lord Mayor Treloar College, Alton, Hampshire, England
,
J. M Matthews
1   Oxford Haemophilia Centre Churchill Hospital, Oxford
2   Lord Mayor Treloar College, Alton, Hampshire, England
,
C. R McLennan
1   Oxford Haemophilia Centre Churchill Hospital, Oxford
2   Lord Mayor Treloar College, Alton, Hampshire, England
,
S. G Rainsford
1   Oxford Haemophilia Centre Churchill Hospital, Oxford
2   Lord Mayor Treloar College, Alton, Hampshire, England
› Author Affiliations
Further Information

Publication History

Received 06 September 1976

Accepted 16 September 1976

Publication Date:
24 July 2018 (online)

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Summary

A double-blind controlled study was carried out to investigate the effectiveness of treatment with factor VIII or factor IX concentrate and a reducing dose of prednisolone in controlling haematuria in patients with haemophilia and Christmas disease.

41 episodes of haematuria were studied in 30 different patients. No appreciable benefit was observed in the treated, as compared with the control group and this is at variance with the results of the few studies reported elsewhere.

* Present Address: Dr. P. B. A. Kernoff, The University of Leeds, Department of Medicine, The Martin Wing, The General Infirmary, Leeds, LSl 3EX.


 

  • References

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