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Thromb Haemost 1977; 37(03): 407-412
DOI: 10.1055/s-0038-1649248
Original Article
Schattauer GmbH

Calcium Electrode – a Method for the Continuous Monitoring of the Platelet Release Reaction

Lois S Robblee
1   Departments of Biology and Surgery. Boston University, Boston, Mass., U.S.A.
,
Laura B Kornstein
1   Departments of Biology and Surgery. Boston University, Boston, Mass., U.S.A.
,
David Shepro
1   Departments of Biology and Surgery. Boston University, Boston, Mass., U.S.A.
› Author Affiliations
Further Information

Publication History

Received 20 December 1976

Accepted 10 January 1977

Publication Date:
03 July 2018 (online)

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Summary

The calcium electrode is a convenient, inexpensive, and non-traumatic method for measuring changes in the extracellular calcium which accompanies a platelet release reaction. With this instrument, the temporal pattern of release by platelets in a buffered-saline medium following thrombin stimulation was observed as follows: an initial time lag phase, followed by a maximum release phase, and finally a slow release phase.

 

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