Thromb Haemost 1977; 37(03): 444-450
DOI: 10.1055/s-0038-1649253
Original Article
Schattauer GmbH

Marathon Run I: Effects on Blood Coagulation and Fibrinolysis

T Mandalaki
1   2nd Regional Blood Transfusion Centre of Athens, Hospital Vassilefs Pavlos, Athens (Goudi) Greece, and The Minerva Foundation Institute for Medical Research, Endocrine Research Laboratory, University of Helsinki, Finland
,
A Dessypris
1   2nd Regional Blood Transfusion Centre of Athens, Hospital Vassilefs Pavlos, Athens (Goudi) Greece, and The Minerva Foundation Institute for Medical Research, Endocrine Research Laboratory, University of Helsinki, Finland
,
C Louizou
1   2nd Regional Blood Transfusion Centre of Athens, Hospital Vassilefs Pavlos, Athens (Goudi) Greece, and The Minerva Foundation Institute for Medical Research, Endocrine Research Laboratory, University of Helsinki, Finland
,
I Bossinakou
1   2nd Regional Blood Transfusion Centre of Athens, Hospital Vassilefs Pavlos, Athens (Goudi) Greece, and The Minerva Foundation Institute for Medical Research, Endocrine Research Laboratory, University of Helsinki, Finland
,
C Panayotopoulou
1   2nd Regional Blood Transfusion Centre of Athens, Hospital Vassilefs Pavlos, Athens (Goudi) Greece, and The Minerva Foundation Institute for Medical Research, Endocrine Research Laboratory, University of Helsinki, Finland
,
A Antonopoulou
1   2nd Regional Blood Transfusion Centre of Athens, Hospital Vassilefs Pavlos, Athens (Goudi) Greece, and The Minerva Foundation Institute for Medical Research, Endocrine Research Laboratory, University of Helsinki, Finland
› Author Affiliations
Further Information

Publication History

Received 31 January 1977

Accepted 06 February 1977

Publication Date:
03 July 2018 (online)

Zoom Image

Summary

Blood coagulation and fibrinolysis were assessed in 13 Finnish amateur runners aged 31 to 48, and one 65-year old taking part in a non-competitive marathon (42.2 km). After the run the mean values of partial thromboplastin time showed a very significant shortening, whereas the mean values of the prothrombin time and of plasma fibrinogen were not significantly altered. The mean values of euglobulin lysis time were significantly shorter and the mean values of fibrin degradation products increased highly significantly. After the run, protamine sulphate was positive or strongly positive in all subjects, whereas the ethanol gelation test was negative in all runners; no cryofibrinogen was detected in any participant. Thus, running a marathon race affects the haemostatic balance and activates the fibrinolytic mechanism. The effects of training and physical fitness on the above parameters are discussed.