Marathon Run II: Effects on Platelet Aggregation

C Dimitriadou; A Dessypris; C Louizou; T Mandalaki

doi:10.1055/s-0038-1649254

Thrombosis and Haemostasis, Table of Contents

Thromb Haemost 1977; 37(03): 451-455
DOI: 10.1055/s-0038-1649254

Original Article

Schattauer GmbH

Marathon Run II: Effects on Platelet Aggregation

Authors

C Dimitriadou

¹2nd Regional Blood Transfusion Centre of Athens, Hospital Vassilefs Pavlos, Athens (Goudi), Greece, and The Minerva Foundation Institute for Medical Research, Endocrine Research Laboratory, University of Helsinki, Finland
A Dessypris

¹2nd Regional Blood Transfusion Centre of Athens, Hospital Vassilefs Pavlos, Athens (Goudi), Greece, and The Minerva Foundation Institute for Medical Research, Endocrine Research Laboratory, University of Helsinki, Finland
C Louizou

¹2nd Regional Blood Transfusion Centre of Athens, Hospital Vassilefs Pavlos, Athens (Goudi), Greece, and The Minerva Foundation Institute for Medical Research, Endocrine Research Laboratory, University of Helsinki, Finland
T Mandalaki

¹2nd Regional Blood Transfusion Centre of Athens, Hospital Vassilefs Pavlos, Athens (Goudi), Greece, and The Minerva Foundation Institute for Medical Research, Endocrine Research Laboratory, University of Helsinki, Finland

Abstract

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Summary

Platelet count and aggregation were assessed in 9 Finnish amateur runners aged 34 to 48, and one 65-year old taking part in a non-competitive marathon race (42.2 km).

After the run the mean value of platelet count showed a very significant rise (p <0.001). The platelets were markedly more sensitive to both ADP and collagen-induced aggregation. A highly significant increase (p <0.001) was noted for both the intensity and velocity of platelet aggregation.

The finding of platelet hyperaggregability after prolonged strenuous exercise even in trained subjects is discussed. It is concluded that a thorough medical examination of the haemostatic balance is recommended before a marathon race.

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References

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