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CC BY-NC-ND 4.0 · Indian Journal of Neurosurgery 2018; 07(01): 001-004
DOI: 10.1055/s-0038-1649524
Special Article - Brief Communication
Thieme Medical and Scientific Publishers Private Ltd.

Pineal Gland—A Spiritual Third Eye: An Odyssey of Antiquity to Modern Chronomedicine

Raj Kumar
1   Department of Neurosurgery, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
,
Arushi Kumar
1   Department of Neurosurgery, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
,
Jayesh Sardhara
1   Department of Neurosurgery, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
› Author Affiliations
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Publication History

Received: 14 January 2018

accepted after revision: 06 March 2018

Publication Date:
25 May 2018 (online)

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Abstract

Pineal gland or “spiritual third eye” is regarded as the gateway of spiritual life as per ancient concepts about the soul. Recently, modern neuroscience has proven that pineal gland is not only the melatonin-secreting neuroendocrine organ which controls the circardian rhythm, but it also has mystical and energetic associations with spirituality. It acts as a tremendous coordinator between molecular, hormonal, physiological, and chemical rhythmic orchestra. Thus, in this article, by highlighting the relation between ancient Indian methodology and modern chronomedicine, the author describes the odyssey of antiquity to modern science.

Keywords

pineal gland - third eye - chronomedicine
 

  • References

  • 1 Jangir OP, Suthar P, Shekhawat DV, Acharya P, Swami KK, Sharma M. The “third eye”—a new concept of trans-differentiation of pineal gland into median eye in amphibian tadpoles of Bufo melanostictus. Indian J Exp Biol 2005; 43 (08) 671-678
    PubMedGoogle Scholar
  • 2 López-Muñoz F, Rubio G, Molina JD, Alamo C. [The pineal gland as physical tool of the soul faculties: a persistent historical connection] [in Spanish]. Neurologia 2012; 27 (03) 161-168
    CrossrefPubMedGoogle Scholar
  • 3 Ashok AH, Baugh J, Yeragani VK. Paul Eugen Bleuler and the origin of the term schizophrenia (SCHIZOPRENIEGRUPPE). Indian J Psychiatry 2012; 54 (01) 95-96
    CrossrefPubMedGoogle Scholar
  • 4 Prus R. Aristotle's theory of deviance and contemporary symbolic interactionist scholarship: learning from the past, extending the present, and engaging the future. Am Sociol 2015; 46 (01) 122-167
    CrossrefPubMedGoogle Scholar
  • 5 Hankey A. Establishing the scientific validity of Tridosha part 1: Doshas, Subdoshas and Dosha Prakritis. Anc Sci Life 2010; 29 (03) 6-18
    PubMedGoogle Scholar
  • 6 Srinivasan TM. Pranayama and brain correlates. Anc Sci Life 1991; 11 (01) (02) 2-6
    PubMedGoogle Scholar
  • 7 Lefta M, Wolff G, Esser KA. Circadian rhythms, the molecular clock, and skeletal muscle. Curr Top Dev Biol 2011; 96: 231-271
    PubMedGoogle Scholar
  • 8 Arora D, Kumar M. Concept of chronopharmacology in ayurveda. Anc Sci Life 2000; 19 (03) (04) 155-163
    PubMedGoogle Scholar
  • 9 Borjigin J, Zhang LS, Calinescu A-A. Circadian regulation of pineal gland rhythmicity. Mol Cell Endocrinol 2012; 349 (01) 13-19
    CrossrefPubMedGoogle Scholar
  • 10 Hardeland R. Neurobiology, pathophysiology, and treatment of melatonin deficiency and dysfunction. Sci World J 2012; 2012: 640389
    PubMedGoogle Scholar
  • 11 Evans JA, Gorman MR. In synch but not in step: circadian clock circuits regulating plasticity in daily rhythms. Neuroscience 2016; 320: 259-280
    CrossrefPubMedGoogle Scholar
  • 12 Morin LP. Neuroanatomy of the extended circadian rhythm system. Exp Neurol 2013; 243: 4-20
    CrossrefPubMedGoogle Scholar
  • 13 Reiter RJ, Rosales-Corral S, Coto-Montes A. et al. The photoperiod, circadian regulation and chronodisruption: the requisite interplay between the suprachiasmatic nuclei and the pineal and gut melatonin. J Physiol Pharmacol 2011; 62 (03) 269-274
    PubMedGoogle Scholar
  • 14 Erren TC, Falaturi P, Morfeld P, Knauth P, Reiter RJ, Piekarski C. Shift work and cancer: the evidence and the challenge. Dtsch Arztebl Int 2010; 107 (38) 657-662
    PubMedGoogle Scholar
  • 15 Joshi A, Mehta CS, Dave AR, Shukla VD. Clinical effect of Nirgundi Patra pinda sweda and Ashwagandhadi Guggulu Yoga in the management of Sandhigata Vata (osteoarthritis). Ayu 2011; 32 (02) 207-212
    CrossrefPubMedGoogle Scholar
  • 16 Rajani A, Vyas MK, Vyas HA. Comparative study of Upavasa and Upavasa with Pachana in the management of Agnisada. Ayu 2010; 31 (03) 351-354
    CrossrefPubMedGoogle Scholar
  • 17 Turget M, Kumar R. The Pineal Gland and Melatonin: Recent Advances in Development, Imaging, Disease, and Treatment. Illustrated ed. Endocrinology Research and Clinical Developments. New York, NY: Nova Science Publishers; 2012
    Google Scholar