Inherited Homozygous Resistance to Activated Protein C

Thromb Haemost 1995; 74(02): 794-795
DOI: 10.1055/s-0038-1649816

Letter to the Editor

Schattauer GmbH Stuttgart

Piedad Villa

¹Departamento de Biopathología Clínica y, Hospital Universitario “La Fé”, Valencia, España

,

Justo Aznar

¹Departamento de Biopathología Clínica y, Hospital Universitario “La Fé”, Valencia, España

,

Juan Jorquera

²Unidad de Coagulopatías Congénitas, Hospital Universitario “La Fé”, Valencia, España

,

Yolanda Mira

¹Departamento de Biopathología Clínica y, Hospital Universitario “La Fé”, Valencia, España

,

Amparo Vayá

¹Departamento de Biopathología Clínica y, Hospital Universitario “La Fé”, Valencia, España

,

MA Fernández

¹Departamento de Biopathología Clínica y, Hospital Universitario “La Fé”, Valencia, España

References
1 Dahlbäck B, Carlsson M, Svensson PJ. Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C. Prediction of a cofactor to activated protein C Proc Natl Acad Sci (USA) 1993; 90: 1004-1008
2 Svensson PJ, Dahlbäck B. Resistance to activated protein C as a basis for venous thrombosis. N Engl J Med 1994; 330: 517-522
3 Koster T, Rosendaal FR, de Ronde H, Briët E, Vanderbroucke JP, Bertina RM. Venous thrombosis due to poor anticoagulant response to activated protein C: Leiden Thrombophilia Study. Lancet 1994; 342: 1503-1506
4 Bertina RM, Koeleman BP C, Koster T, Rosendaal FR, Dirven RJ, de Ronde FI, van der Velden PA, Reitsma PH. Mutation in blood coagulation factor V associated with resistance to activated protein C. Nature 1994; 369: 64-67
5 Jorquera JI, Montoro JM, Fernández MA, Aznar JA, Aznar J. Modified test for activated protein C resistance. Lancet 1994; 344: 1162-1163