Absence of In Vitro Cross-Reaction of Pentasaccharide with the Plasma Heparin-Dependent Factor of Twenty-Five Patients with Heparin-Associated Thrombocytopenia

I Elalamy; C Lecrubier; F Potevin; M Abdelouahed; L Bara; J P Marie; M M Samama

doi:10.1055/s-0038-1649949

Thrombosis and Haemostasis, Table of Contents

Thromb Haemost 1995; 74(05): 1384-1385
DOI: 10.1055/s-0038-1649949

Letter To The Editor

Schattauer GmbH Stuttgart

Absence of In Vitro Cross-Reaction of Pentasaccharide with the Plasma Heparin-Dependent Factor of Twenty-Five Patients with Heparin-Associated Thrombocytopenia

I Elalamy

The Service d’Hématologie Biologique, Hôpital Hôtel-Dieu, Paris, France

,

C Lecrubier

The Service d’Hématologie Biologique, Hôpital Hôtel-Dieu, Paris, France

,

F Potevin

The Service d’Hématologie Biologique, Hôpital Hôtel-Dieu, Paris, France

,

M Abdelouahed

The Service d’Hématologie Biologique, Hôpital Hôtel-Dieu, Paris, France

,

L Bara

The Service d’Hématologie Biologique, Hôpital Hôtel-Dieu, Paris, France

,

J P Marie

The Service d’Hématologie Biologique, Hôpital Hôtel-Dieu, Paris, France

,

M M Samama

The Service d’Hématologie Biologique, Hôpital Hôtel-Dieu, Paris, France

› Author Affiliations

Abstract

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References

References
1 Chong BH. Heparin-induced thrombocytopenia. Brit J Haemat 1995; 89: 431-439
2 Kelton JG, Sheridan D, Santos A, Smith J, Steeves K, Smith C, Brown C, Murphy WG. Heparin-indueed thrombocytopenia: laboratory studies. Blood 1988; 72: 925-930
3 Fratantoni JC, Pollet R, Gralniek HR. Heparin-indueed thrombocytopenia: confirmation of diagnosis with in vitro method. Blood 1975; 45: 395-401
4 Orgaran. 13th Congress of the International Society of Thrombosis and Haemostasis. Haemost 1992; 22: 57-112
5 Béguin S, Choay J, Hemker HC. The action of a synthetic pentasaccharide on thrombin. Thromb Haemost 1989; 61 (03) 397-401
6 Lecrubier C, Lecompte T, Potevin F, Horellou MH, Conard J, Samama M. Tests d’agrégation plaquettaire dans 26 cas de thrombopénies induites parlPhdparinc (TIH). Probl&mes méthodologiques, diagnostiques et aspects thérapeutiques J Mal Vase 1987; 12: 128-132
7 Kelton JG, Sheridan D, Brain H, Powers PJ, Turpie AG, Carter CJ. Clinical usefulness of testing for a heparin-dependent platelet aggregating factor in patients with suspected heparin-associated-thrombocytopenia. J Lab Clin Med 1984; 103: 606-612
8 Lecompte T, Stieltjes N, Noiray B, Luo SK, Farkas JC, Morel-Kopp MC, Kaplan C, Samama MM. Variability of the response of human platelets to activating monoclonal antibodies: relevance to the in vitro aggregation test for heparin-induced thrombocytopenia. Zimmerman Conference. Progress in vascular biology Haemostasis and Thrombosis. La Jolla; California:
9 ZuZel M, Walton S, Burns GF, Berndt MC, Cawley JC. A monoclonal antibody to a 67 kD cell membrane glycoprotein directly induces persistent platelet aggregation independently of granule secretion. Brit J Haemat 1991; 79: 466-473
10 Gerotziafas G, Lecrubier C, Lebrazi J, Elalamy I, Kaplan C, Samama MM, Lecompte T. Immunological human platelet activation induced by two monoclonal antibodies: PL2-49 and LeoAl. Submitted.
11 Chong BH, Ismail F, Cade J, Gallus AS, Gordon S, Chesterman C. Heparin-associated thrombocytopenia: studies with a new low-molecular weight heparinoid, Orgl9172. Blood 1989; 73: 1592-1596