An Attempt at Predicting Postoperative Deep Vein Thrombosis by Preoperative Coagulation Studies in Patients Undergoing Total Hip Replacement

Dennis W T Nilsen; Miladin Jeremic; Odd K Weisert

doi:10.1055/s-0038-1650050

Thrombosis and Haemostasis, Table of Contents

Thromb Haemost 1980; 43(03): 194-197
DOI: 10.1055/s-0038-1650050

Original Article

Schattauer GmbH Stuttgart

An Attempt at Predicting Postoperative Deep Vein Thrombosis by Preoperative Coagulation Studies in Patients Undergoing Total Hip Replacement

Dennis W T Nilsen

The Oslo Emergency Medical Centre, University Hospital of Ullevål, Oslo and State Laboratory of Microbiology, Department of Immunohaematology and Blood Transfusion, Lillehammer, Norway

,

Miladin Jeremic

The Oslo Emergency Medical Centre, University Hospital of Ullevål, Oslo and State Laboratory of Microbiology, Department of Immunohaematology and Blood Transfusion, Lillehammer, Norway

,

Odd K Weisert

The Oslo Emergency Medical Centre, University Hospital of Ullevål, Oslo and State Laboratory of Microbiology, Department of Immunohaematology and Blood Transfusion, Lillehammer, Norway

› Author Affiliations

Abstract

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Summary

Preoperative levels of fibrinogen, factors V, VII, VIII and antithrombin III were measured in 25 consecutive patients undergoing total hip replacement. Deep vein thrombosis (D.V.T.) was detected by fibrinogen-uptake test in 60% of the patients. The preoperative fibrinogen level was significantly higher (p < 0.05), and serum antithrombin III was markedly lower (p ≦ 0.1) in patients with postoperative D.V.T. The quotient of fibrinogen to serum antithrombin III was significantly higher (p < 0.01) in patients with D.V.T. This quotient may serve as an additional parameter to other clinical and laboratory tests in prediction of postoperative D.V.T. following hip surgery.

Keywords

Preoperative coagulation factors - Postoperative thrombosis in hip surgery

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References

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