Warfarin Induced Skin Necrosis Associated with Activated Protein C Resistance

Thromb Haemost 1996; 75(03): 523-524
DOI: 10.1055/s-0038-1650312

Letter to the Editor

Schattauer GmbH Stuttgart

Authors

M Makris

The Departments of Haematology, Doncaster Royal Infirmary and Royal Hallamshire Hospital, Sheffield, UK
G Bardhan

The Departments of Haematology, Doncaster Royal Infirmary and Royal Hallamshire Hospital, Sheffield, UK
F E Preston

The Departments of Haematology, Doncaster Royal Infirmary and Royal Hallamshire Hospital, Sheffield, UK

References
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2 Craig A, Taberner DA, Fisher AH, Foster DN, Mitra J. Type I protein S deficiency and skin necrosis. Postgraduate Med J 1990; 66: 389-391
3 Cole MS, Minifee PK, Wolma FJ. Coumarin necrosis-A review of the literature. Surgery 1988; 103: 271-277
4 Koster T, Rosendaal FR, de Ronde H, Briet E, Vandenbroucke JP, Bertina RM. Venous thrombosis due to poor anticoagulant response to activated protein C: Leiden thrombophilia study. Lancet 1993; 342: 1503-1506
5 Bertina MR, Koeleman BPC, Koster T, Rosendaal FR, Diwen RJ, De Ronde H, van der Velden PA, Reitsma PH. Mutation in blood coagulation factor V associated with resistance to activated protein C. Nature 1994; 369: 64-67