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Thromb Haemost 1969; 22(03): 508-512
DOI: 10.1055/s-0038-1651387
Originalarbeiten-Original Articles-Travaux Originaux
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Reticuloendothelial Function and Blood Coagulation in Rats

L Pechet
1   Departments of Pathology and Medicine, Boston University School of Medicine, and the Boston Veterans Administration Hospital, 150 South Huntington Avenue, Boston, Massachusetts, 02130
,
Giselle S. Pechet
1   Departments of Pathology and Medicine, Boston University School of Medicine, and the Boston Veterans Administration Hospital, 150 South Huntington Avenue, Boston, Massachusetts, 02130
,
R. A MacDonald
1   Departments of Pathology and Medicine, Boston University School of Medicine, and the Boston Veterans Administration Hospital, 150 South Huntington Avenue, Boston, Massachusetts, 02130
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Publication Date:
10 June 2018 (online)

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Summary

Intravascular coagulation and its possible effect on carbon clearance was studied in rats following the injection of commercial india ink containing shellac; a shellac-free carbon preparation; gelatin; heat denatured albumin; colloidal iron; and heparin. No relationship was found between activation of coagulation and RES function as measured by clearance of intravenously injected carbon.

 

  • References

  • 1 Prose P. H, Lee L, Balk S. D. Electron microscopic study of the phagocytic fibrin-clearing mechanism. Amer. J. Path. 47: 403 1965;
    PubMedSearch in Google Scholar
  • 2 Lee L. Reticuloendothelial clearance of circulating fibrin in the pathogenesis of the generalized Schwartzman Reaction. J. exp. Med. 115: 1065 1962;
    CrossrefPubMedSearch in Google Scholar
  • 3 Filkins J. P, DiLuzio N. R. Effects of gelatin and heparin on intravascular phagocytosis. J. reticuloend. Soc. 3: 471 1966;
    PubMedSearch in Google Scholar
  • 4 Halperri B. N, Benacerraf B, Biozzi G. Quantitative study of the granulopectic activity of the reticuloendothelial system. I. The effect of the ingredients present in india ink and of substances affecting blood clotting in vivo on the fate of carbon particles administered intravenously in rats, mice and rabbits. Brit. J. exp. Path. 34: 426 1953;
    PubMedSearch in Google Scholar
  • 5 Normann S. J, Benditi E. P. Function of the reticuloendothelial system. I. A study of the phenomenon of carbon clearance inhibition. J. exp. Med. 122: 693 1965;
    CrossrefPubMedSearch in Google Scholar
  • 6 lio M, Wagner H. N. Studies of the reticuloendothelial system. Measurement of the phagocytic capacity of the RES in man and dog. J. clin. Inv. 42: 417 1963;
    CrossrefPubMedSearch in Google Scholar
  • 7 Pechet L, Cochios F, Deykin D. Further studies on the “Dyniá” clotting abnormality. Thrombos. Diathes. haemorrh. (Stuttg.) 17: 365 1967;
    PubMedSearch in Google Scholar
  • 8 Ratnoff O. D, Menzie C. A new method for the determination of fibrinogen in small samples of plasma. J. Lab. clin. Med. 37: 316 1951;
    PubMedSearch in Google Scholar
  • 9 Sawyer W. D, Alkjaersig N, Fletcher A. P, Sherry S. A comparison of the fibrinolytic and fibrinogenolytic effects of plasminogen activators and proteolytic enzymes in plasma. Thrombos. Diathes. haemorrh. (Stuttg.) 5: 149 1960;
    PubMedSearch in Google Scholar
  • 10 Millstone H. A factor in normal human blood which participates in streptococcal fibrinolysis. J. Immunol. 42: 109 1941;
    PubMedSearch in Google Scholar
  • 11 Biozzi B, Benacerraf B, Menne G, Holpern B. N. Etude quantitative de l’activite granulo-pexique du systeme reticulo-endothelial par l’injection intraveineuse d’encre de Chine chez les diverses especes animales. II. Relations entre les modifications de la coagulation du sang in vitro sous l’effet de l’injection intraveineuse de doses croissantes d’encre de Chine et sa repartition dan l’organisme. Ann. Inst. Pasteur. 81: 164 1951;
    PubMedSearch in Google Scholar
  • 12 Gabrieli E. R, Pyzikiewicz T, Mlodozeniec P. Comment on the india ink clearance as a reticuloendothelial test. J. reticuloend. Soc. 4: 223 1967;
    PubMedSearch in Google Scholar